Live-cell time-lapse imaging of somatic cells undergoing reprogramming raises interesting questions about the mechanism of the process.
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References
Smith, Z.D. et al. Dynamic single-cell imaging of direct reprogramming reveals an early specifying event. Nat. Biotechnol. 5, 521–526 (2010).
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de Souza, N. Where do you come from?. Nat Methods 7, 488–489 (2010). https://doi.org/10.1038/nmeth0710-488b
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DOI: https://doi.org/10.1038/nmeth0710-488b