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Vectors allowing hydrophilic compounds to gain access to the cell interior are needed to reach new therapeutic targets. Transduction peptides have opened the way to this, but their chemical mimics may be of even greater interest.
Cellular imaging by fluorescence microscopy is becoming simultaneously higher-throughput and more quantitative as researchers develop integrated systems for image acquisition and analysis.
From mutagenesis to gene therapy for hemophilia, transposons—mobile genetic elements—have proven themselves innovative tools in the laboratory and the clinic. Caitlin Smith takes a look at some present offerings of transposon products and the promise of applications.