Vectors allowing hydrophilic compounds to gain access to the cell interior are needed to reach new therapeutic targets. Transduction peptides have opened the way to this, but their chemical mimics may be of even greater interest.
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Prochiantz, A. For protein transduction, chemistry can win over biology. Nat Methods 4, 119–120 (2007). https://doi.org/10.1038/nmeth0207-119
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DOI: https://doi.org/10.1038/nmeth0207-119
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The P42 peptide and Peptide-based therapies for Huntington’s disease
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