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Poker face no more: cancer recurrence reveals its hand

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Recurrent disease after apparent 'cure' of primary tumors is a common factor that contributes to cancer-associated mortality. A new study suggests that an inflammatory cytokine signature may provide a clinical indication of emergent recurrent disease and, accordingly, may suggest how to select and deliver therapy targeted against the secondary tumor (pages 1625–1631).

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Figure 1: Systemic VEGF and IL-6 are functional indicators of early recurrent disease in cancer.

Katie Vicari

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Correspondence to Lisa M Coussens.

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Chan, C., Coussens, L. Poker face no more: cancer recurrence reveals its hand. Nat Med 19, 1569–1570 (2013). https://doi.org/10.1038/nm.3410

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