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Sex differences in the prevalence, risk factors and symptoms of cardiometabolic disorders are being elucidated and should be taken into account in diagnosis and treatment.
The rise of cardiometabolic diseases in low- and middle-income countries is tied to a multitude of environmental, social and commercial determinants, which are discussed in this Review along with a strategy to counteract those factors.
Clinical application of CAR T cells to cancer therapy has met with much success, but future trials must build on current understanding to overcome therapy resistance
Childhood cancers are developmentally distinct from adult cancers and arise from cellular reprogramming as a result of epigenetic mutations or gene fusions, providing unique therapeutic opportunities.
The universal flu vaccine remains elusive, but there are several strategies that scientists can take to develop one, including closer monitoring of viral evolution.
The increased amount of health care data collected brings with it ethical and legal challenges for protecting the patient while optimizing health care and research.
Artificial intelligence is beginning to be applied in the medical setting and has potential to improve workflows and errors, impacting patients and clinicians alike.