Marina Spence and Hannah Stower

Focus on COVID-19 and digital privacy

This focus of Reviews, Perspectives and comments considers the myriad ways in which digital applications have been applied in the pandemic and the spectrum of privacy concerns for health data.

Latest Research

  • Article |

    In a phase II clinical trial of patients with classical Hodgkin lymphoma, peripheral CD4+ T cell receptor diversity and the abundance of mature natural killer cells and CD3CD68+CD4+GrB+ innate cells were associated with favorable responses to anti-PD-1 monotherapy.

    • Fathima Zumla Cader
    • , Xihao Hu
    • , Walter L. Goh
    • , Kirsty Wienand
    • , Jing Ouyang
    • , Elisa Mandato
    • , Robert Redd
    • , Lee N. Lawton
    • , Pei-Hsuan Chen
    • , Jason L. Weirather
    • , Ron C. J. Schackmann
    • , Bo Li
    • , Wenjiang Ma
    • , Philippe Armand
    • , Scott J. Rodig
    • , Donna Neuberg
    • , X. Shirley Liu
    •  & Margaret A. Shipp
  • Brief Communication |

    Integration of large datasets of familial whole-exome sequencing, neurodevelopmental gene expression, electronic health records and healthcare claims led to the identification of a subtype of autism spectrum disorder that is associated with lipid dysregulation.

    • Yuan Luo
    • , Alal Eran
    • , Nathan Palmer
    • , Paul Avillach
    • , Ami Levy-Moonshine
    • , Peter Szolovits
    •  & Isaac S. Kohane
  • Letter |

    In a cohort of nearly half a million births in Ontario, Canada, maternal cannabis use in pregnancy was associated with an increased incidence of autism spectrum disorder diagnosis in the offspring.

    • Daniel J. Corsi
    • , Jessy Donelle
    • , Ewa Sucha
    • , Steven Hawken
    • , Helen Hsu
    • , Darine El-Chaâr
    • , Lise Bisnaire
    • , Deshayne Fell
    • , Shi Wu Wen
    •  & Mark Walker
  • Letter |

    Whole-exome sequencing is not sensitive or specific enough to replace the gold standard of tandem mass spectrometry screening of rare inborn errors of metabolism, but can help to reduce false positives and facilitate the timely resolution of ambiguous cases.

    • Aashish N. Adhikari
    • , Renata C. Gallagher
    • , Yaqiong Wang
    • , Robert J. Currier
    • , George Amatuni
    • , Laia Bassaganyas
    • , Flavia Chen
    • , Kunal Kundu
    • , Mark Kvale
    • , Sean D. Mooney
    • , Robert L. Nussbaum
    • , Savanna S. Randi
    • , Jeremy Sanford
    • , Joseph T. Shieh
    • , Rajgopal Srinivasan
    • , Uma Sunderam
    • , Hao Tang
    • , Dedeepya Vaka
    • , Yangyun Zou
    • , Barbara A. Koenig
    • , Pui-Yan Kwok
    • , Neil Risch
    • , Jennifer M. Puck
    •  & Steven E. Brenner
  • Letter |

    Transmission dynamics models of COVID-19 and malaria reveal how different scenarios of COVID-19 spread and varying levels of interruption to antimalarial programs could result in increased deaths in sub-Saharan Africa.

    • Ellie Sherrard-Smith
    • , Alexandra B. Hogan
    • , Arran Hamlet
    • , Oliver J. Watson
    • , Charlie Whittaker
    • , Peter Winskill
    • , Fatima Ali
    • , Audu B. Mohammad
    • , Perpetua Uhomoibhi
    • , Ibrahim Maikore
    • , Nnenna Ogbulafor
    • , Jamilu Nikau
    • , Mara D. Kont
    • , Joseph D. Challenger
    • , Robert Verity
    • , Ben Lambert
    • , Matthew Cairns
    • , Bhargavi Rao
    • , Marc Baguelin
    • , Lilith K. Whittles
    • , John A. Lees
    • , Sangeeta Bhatia
    • , Edward S. Knock
    • , Lucy Okell
    • , Hannah C. Slater
    • , Azra C. Ghani
    • , Patrick G. T. Walker
    • , Okefu Oyale Okoko
    •  & Thomas S. Churcher
  • Letter |

    In a study of children with high genetic risk aged 2 years or older, a risk score integrating pancreatic islet autoantibodies, genetic factors and family history is highly predictive of type 1 diabetes in the subsequent 8 years.

    • Lauric A. Ferrat
    • , Kendra Vehik
    • , Seth A. Sharp
    • , Åke Lernmark
    • , Marian J. Rewers
    • , Jin-Xiong She
    • , Anette-G. Ziegler
    • , Jorma Toppari
    • , Beena Akolkar
    • , Jeffrey P. Krischer
    • , Michael N. Weedon
    • , Richard A. Oram
    • , William A. Hagopian
    • , Aaron Barbour
    • , Kimberly Bautista
    • , Judith Baxter
    • , Daniel Felipe-Morales
    • , Kimberly Driscoll
    • , Brigitte I. Frohnert
    • , Marisa Stahl
    • , Patricia Gesualdo
    • , Michelle Hoffman
    • , Rachel Karban
    • , Edwin Liu
    • , Jill Norris
    • , Stesha Peacock
    • , Hanan Shorrosh
    • , Andrea Steck
    • , Megan Stern
    • , Erica Villegas
    • , Kathleen Waugh
    • , Olli G. Simell
    • , Annika Adamsson
    • , Suvi Ahonen
    • , Mari Åkerlund
    • , Leena Hakola
    • , Anne Hekkala
    • , Henna Holappa
    • , Heikki Hyöty
    • , Anni Ikonen
    • , Jorma Ilonen
    • , Sinikka Jäminki
    • , Sanna Jokipuu
    • , Leena Karlsson
    • , Jukka Kero
    • , Miia Kähönen
    • , Mikael Knip
    • , Minna-Liisa Koivikko
    • , Merja Koskinen
    • , Mirva Koreasalo
    • , Kalle Kurppa
    • , Jarita Kytölä
    • , Tiina Latva-aho
    • , Katri Lindfors
    • , Maria Lönnrot
    • , Elina Mäntymäki
    • , Markus Mattila
    • , Maija Miettinen
    • , Katja Multasuo
    • , Teija Mykkänen
    • , Tiina Niininen
    • , Sari Niinistö
    • , Mia Nyblom
    • , Sami Oikarinen
    • , Paula Ollikainen
    • , Zhian Othmani
    • , Sirpa Pohjola
    • , Petra Rajala
    • , Jenna Rautanen
    • , Anne Riikonen
    • , Eija Riski
    • , Miia Pekkola
    • , Minna Romo
    • , Satu Ruohonen
    • , Satu Simell
    • , Maija Sjöberg
    • , Aino Stenius
    • , Päivi Tossavainen
    • , Mari Vähä-Mäkilä
    • , Sini Vainionpää
    • , Eeva Varjonen
    • , Riitta Veijola
    • , Irene Viinikangas
    • , Suvi M. Virtanen
    • , Desmond Schatz
    • , Diane Hopkins
    • , Leigh Steed
    • , Jennifer Bryant
    • , Katherine Silvis
    • , Michael Haller
    • , Melissa Gardiner
    • , Richard McIndoe
    • , Ashok Sharma
    • , Stephen W. Anderson
    • , Laura Jacobsen
    • , John Marks
    • , P. D. Towe
    • , Ezio Bonifacio
    • , Cigdem Gezginci
    • , Anja Heublein
    • , Eva Hohoff
    • , Sandra Hummel
    • , Annette Knopff
    • , Charlotte Koch
    • , Sibylle Koletzko
    • , Claudia Ramminger
    • , Roswith Roth
    • , Jennifer Schmidt
    • , Marlon Scholz
    • , Joanna Stock
    • , Katharina Warncke
    • , Lorena Wendel
    • , Christiane Winkler
    • , Daniel Agardh
    • , Carin Andrén Aronsson
    • , Maria Ask
    • , Rasmus Bennet
    • , Corrado Cilio
    • , Susanne Dahlberg
    • , Helene Engqvist
    • , Emelie Ericson-Hallström
    • , Annika Björne Fors
    • , Lina Fransson
    • , Thomas Gard
    • , Monika Hansen
    • , Hanna Jisser
    • , Fredrik Johansen
    • , Berglind Jonsdottir
    • , Helena Elding Larsson
    • , Marielle Lindström
    • , Markus Lundgren
    • , Marlena Maziarz
    • , Maria Månsson-Martinez
    • , Jessica Melin
    • , Zeliha Mestan
    • , Caroline Nilsson
    • , Karin Ottosson
    • , Kobra Rahmati
    • , Anita Ramelius
    • , Falastin Salami
    • , Anette Sjöberg
    • , Birgitta Sjöberg
    • , Carina Törn
    • , Åsa Wimar
    • , Michael Killian
    • , Claire Cowen Crouch
    • , Jennifer Skidmore
    • , Masumeh Chavoshi
    • , Arlene Meyer
    • , Jocelyn Meyer
    • , Denise Mulenga
    • , Nole Powell
    • , Jared Radtke
    • , Matei Romancik
    • , Shreya Roy
    • , Davey Schmitt
    • , Sarah Zink
    • , Dorothy Becker
    • , Margaret Franciscus
    • , MaryEllen Dalmagro-Elias Smith
    • , Ashi Daftary
    • , Mary Beth Klein
    • , Chrystal Yates
    • , Sarah Austin-Gonzalez
    • , Maryouri Avendano
    • , Sandra Baethke
    • , Brant Burkhardt
    • , Martha Butterworth
    • , Joanna Clasen
    • , David Cuthbertson
    • , Christopher Eberhard
    • , Steven Fiske
    • , Jennifer Garmeson
    • , Veena Gowda
    • , Kathleen Heyman
    • , Belinda Hsiao
    • , Christina Karges
    • , Francisco Perez Laras
    • , Qian Li
    • , Shu Liu
    • , Xiang Liu
    • , Kristian Lynch
    • , Colleen Maguire
    • , Jamie Malloy
    • , Cristina McCarthy
    • , Hemang Parikh
    • , Cassandra Remedios
    • , Chris Shaffer
    • , Laura Smith
    • , Susan Smith
    • , Noah Sulman
    • , Roy Tamura
    • , Dena Tewey
    • , Michael Toth
    • , Ulla Uusitalo
    • , Ponni Vijayakandipan
    • , Keith Wood
    • , Jimin Yang
    • , Liping Yu
    • , Dongmei Miao
    • , Polly Bingley
    • , Alistair Williams
    • , Kyla Chandler
    • , Ilana Kelland
    • , Yassin Ben Khoud
    • , Huma Zahid
    • , Matthew Randell
    • , Masumeh Chavoshi
    • , Jared Radtke
    • , Sarah Zink
    • , Sandra Ke
    • , Niveen Mulholland
    • , Stephen S. Rich
    • , Wei-Min Chen
    • , Suna Onengut-Gumuscu
    • , Emily Farber
    • , Rebecca Roche Pickin
    • , Jonathan Davis
    • , Jordan Davis
    • , Dan Gallo
    • , Jessica Bonnie
    • , Paul Campolieto
    • , Joseph F. Petrosino
    • , Nadim J. Ajami
    • , Richard E. Lloyd
    • , Matthew C. Ross
    • , Jacqueline L. O’Brien
    • , Diane S. Hutchinson
    • , Daniel P. Smith
    • , Matthew C. Wong
    • , Xianjun Tian
    • , Tulin Ayvaz
    • , Auriole Tamegnon
    • , Nguyen Truong
    • , Hannah Moreno
    • , Lauren Riley
    • , Eduardo Moreno
    • , Tonya Bauch
    • , Lenka Kusic
    • , Ginger Metcalf
    • , Donna Muzny
    • , Harshavardhan Doddapaneni
    • , Richard Gibbs
    • , Kasia Bourcier
    • , Thomas Briese
    • , Suzanne Bennett Johnson
    • , Eric Triplett
    • , Anette G. Ziegler
    • , Roy Tamura
    • , Jill Norris
    • , Suvi M. Virtanen
    • , Brigitte I. Frohnert
    • , Patricia Gesualdo
    • , Mirva Koreasalo
    • , Maija Miettinen
    • , Sari Niinistö
    • , Anne Riikonen
    • , Katherine Silvis
    • , Eva Hohoff
    • , Sandra Hummel
    • , Christiane Winkler
    • , Carin Andrén Aronsson
    • , Jennifer Skidmore
    • , MaryEllen Dalmagro-Elias Smith
    • , Martha Butterworth
    • , Qian Li
    • , Xiang Liu
    • , Roy Tamura
    • , Ulla Uusitalo
    • , Jimin Yang
    • , Stephen S. Rich
    • , Jill Norris
    • , Andrea Steck
    • , Jorma Ilonen
    • , Anette G. Ziegler
    • , Carina Törn
    • , Qian Li
    • , Xiang Liu
    • , Hemang Parikh
    • , Henry Erlich
    • , Wei-Min Chen
    • , Suna Onengut-Gumuscu
    • , Desmond Schatz
    • , Anette G. Ziegler
    • , Corrado Cilio
    • , Ezio Bonifacio
    • , Mikael Knip
    • , Desmond Schatz
    • , Brant Burkhardt
    • , Kristian Lynch
    • , Liping Yu
    • , Polly Bingley
    • , Kasia Bourcier
    • , Heikki Hyöty
    • , Eric Triplett
    • , Richard Lloyd
    • , Patricia Gesualdo
    • , Kathleen Waugh
    • , Maria Lönnrot
    • , Daniel Agardh
    • , Corrado Cilio
    • , Helena Elding Larsson
    • , Michael Killian
    • , Brant Burkhardt
    • , Kristian Lynch
    • , Thomas Briese
    • , Kathleen Waugh
    • , Desmond Schatz
    • , Michael Killian
    • , Suzanne Bennett Johnson
    • , Roswith Roth
    • , Judith Baxter
    • , Kimberly Driscoll
    • , Desmond Schatz
    • , Joanna Stock
    • , Steven Fiske
    • , Xiang Liu
    • , Kristian Lynch
    • , Laura Smith
    • , Judith Baxter
    • , Åke Lernmark
    • , Judith Baxter
    • , Michael Killian
    • , Kimberly Bautista
    • , Patricia Gesualdo
    • , Michelle Hoffman
    • , Rachel Karban
    • , Jill Norris
    • , Kathleen Waugh
    • , Annika Adamsson
    • , Miia Kähönen
    • , Tiina Niininen
    • , Aino Stenius
    • , Eeva Varjonen
    • , Diane Hopkins
    • , Leigh Steed
    • , Jennifer Bryant
    • , Melissa Gardiner
    • , John Marks
    • , Claudia Ramminger
    • , Joanna Stock
    • , Christiane Winkler
    • , Carin Andrén Aronsson
    • , Berglind Jonsdottir
    • , Jessica Melin
    • , Michael Killian
    • , Claire Cowen Crouch
    • , Denise Mulenga
    • , Cristina McCarthy
    • , Laura Smith
    • , Susan Smith
    • , Roy Tamura
    • , Suzanne Bennett Johnson
    • , Daniel Agardh
    • , Edwin Liu
    • , Sibylle Koletzko
    • , Kalle Kurppa
    • , Marisa Stahl
    • , Michelle Hoffman
    • , Kalle Kurppa
    • , Katri Lindfors
    • , Satu Simell
    • , Leigh Steed
    • , Carin Andrén Aronsson
    • , Michael Killian
    • , Roy Tamura
    • , Michael Haller
    • , Helena Elding Larsson
    • , Brigitte I. Frohnert
    • , Patricia Gesualdo
    • , Michelle Hoffman
    • , Andrea Steck
    • , Miia Kähönen
    • , Riitta Veijola
    • , Leigh Steed
    • , Laura Jacobsen
    • , John Marks
    • , Joanna Stock
    • , Katharina Warncke
    • , Markus Lundgren
    • , Åsa Wimar
    • , Claire Cowen Crouch
    • , Xiang Liu
    •  & Roy Tamura

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