The cover depicts elements of the integrated artificial intelligence platform that expands the capacity of healthcare providers to visualize and interpret signs of deterioration associated with sepsis.

Sleepwalking into the next pandemic

Governments and funders must prioritize research on emerging and re-emerging infectious diseases such as monkeypox to prevent another pandemic.




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  • Over half of all infectious diseases that affect humans worldwide can be aggravated by climate change, which highlights the urgency of tough climate action and mitigation measures.

    • Karen O’Leary
    Research Highlight
  • Hematopoietic stem-cell gene therapy has proven to be an effective treatment for several primary immunodeficiencies, and yet companies in this space are withdrawing from the EU market. Technological and regulatory innovations and a change to cost–benefit models are needed so that rare disease patients can receive these life-saving medicines.

    • Alessandro Aiuti
    • Francesca Pasinelli
    • Luigi Naldini
  • Ultrasounds can provide a wealth of information on organ function and disease; now scientists have engineered a stick-on wearable ultrasound device for continuous monitoring.

    • Karen O’Leary
    Research Highlight
  • Pfizer had successes during COVID-19 by streamlining decisions and running several steps in parallel, a lightspeed approach that can be applied to other diseases.

    • Annaliesa S. Anderson
    World View

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