Hepatitis B: a new weapon against an old enemy

A first-in-human study of an antisense oligonucleotide targeting hepatitis B virus RNA provides initial insights into this potential therapeutic modality for individuals with chronic HBV infection.

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  • Structure of insulin.

    2021 marks the centenary of the discovery of insulin. This Milestone timeline highlights some of the key advances that have occurred in diabetes research over the past 100 years — from the development of synthetic insulin to new drug classes and technologies for the management of diabetes.

  • Preparing for the next pandemic

    Nature Medicine launches a special Focus dedicated to understanding the long-term impact of the COVID-19 pandemic, and to begin to explore the lessons that can be drawn from the mistakes in handling the current health crisis in order to prepare for future ones.

  • Crab, the avatar of cancer.

    The ancient physician Hippocrates described the projection of blood vessels from a collection of cells as ‘karkinos’, the Greek word for crab. Today, we know this malignant growth as cancer. These Milestones celebrate two decades of breakthroughs in basic, translational and clinical research which have revolutionised our understanding and management of cancer.

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