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The hidden functional diversity of macrophages
Our work identifies previously unrecognized functional heterogeneity in tissue-resident interstitial macrophages. We have identified ten macrophage subsets, each thought to specifically contribute to recruiting and organizing cell types within tissues. Moreover, our findings suggest the diversity and division of labor extend to other macrophage populations previously considered homogeneous.
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Interleukin 31, a cytokine produced by activated T cells, induces dermatitis in mice
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Predictability of B cell clonal persistence and immunosurveillance in breast cancer
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Tissue-resident macrophages
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Breaking NGF–TrkA immunosuppression in melanoma sensitizes immunotherapy for durable memory T cell protection