Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain
the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in
Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles
and JavaScript.
The ENIGMA-ORIGINs group presents a large and globally diverse pediatric neuroimaging dataset from birth to age 6. They use this resource to study the effects of sociodemographics and adverse birth outcomes on trajectories of brain volumes and cognition.
The neuronal subtypes regulating the emotional component of learning and memory are not fully described. Here the authors provide a molecular atlas of the adult mouse amygdala and show the subsets of cells transcriptionally responsive to fear.
The Dominantly Inherited Alzheimer Network neuroimaging repository is a free resource consisting of PET and MRI scans from 533 individuals across 206 families who are deeply phenotyped with genetic, clinical, cognitive and biofluid sampling.
Froudist-Walsh et al. reveal organizational principles of receptor densities in macaque cortex. Densities of multiple receptor types align with changes in dendritic properties, myelin and functional networks. Data are openly released to the community.
By inferring the cellular landscape of the neocortex in 638 aged individuals from RNA profiles, the authors uncovered unique cellular communities composed of coordinated populations of multiple cell types, which were altered in Alzheimer’s disease.
By reconstructing the complete dendrites and axons for nearly 2,000 neurons in PFC, Gao et al. comprehensively classified dendrite morphology, revealed the relationship between dendrites and axons and mapped the mesoscopic PFC neural network.
The authors created a comprehensive developmental cell atlas for spatiotemporal gene expression of the human spinal cord, revealed species-specific regulation during development and used the atlas to infer novel markers for pediatric ependymomas.
Andersen, Thom and colleagues reveal the single-cell-resolution transcriptome of the midgestation human spinal cord and discover remarkable heterogeneity across and within cell types.
The authors pooled resources to identify best practices and develop a new standardized protocol for estimating functional connectivity in rats with magnetic resonance imaging.
Knowing one’s own behavioral state is important to contextualize sensory cues and identify appropriate future actions. Here the authors show how neurons ascending from the fly motor system convey behavioral state signals to specific brain regions.