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The unique electrical, mechanical and physical properties of two-dimensional materials make them attractive candidates in flexible nanoelectronic systems. Here Akinwande et al.review the literature on two-dimensional materials in flexible nanoelectronics, and highlight barriers to their full implementation.
Proteins are subject to continuous and complex quality-control mechanisms, which ensure integrity of the proteome. Vilchez et al.review how a demise in these processes, collectively referred to as proteostasis, is linked to organismal ageing and the development of age-associated diseases.
Carbon mitigation is considered an important and viable pathway towards climate stabilization, but competition for land is high. Here, Canadell and Schulze consider the sustainable implementation of a number of land-based biological carbon mitigation activities and assess the carbon savings achievable by 2050.
Patterns of genomic variation can be used to identify targets of positive selection but understanding their mode of evolution is challenging. This review discusses theory and empirical evidence regarding soft sweep models and concludes that the recent enthusiasm for soft sweeps is unfounded.
Neutrinos are ghost-like particles that interact only very weakly with other particles. As ongoing experiments to measure their properties improve, Ohlsson and Zhou review neutrino mass models and the renormalization group running of neutrino parameters that aim to understand the origin of neutrino mass.
The chemical modification of proteins is an important tool for probing natural systems and synthesizing novel conjugates. Here, Spicer and Davis review the merits and limitations of the most useful methods for selective modification at both natural and unnatural amino acids.
Computer memory based on ferroelectric polarization is a promising alternative to technologies based, for example, on magnetism. Here, Garcia and Bibes review how ferroelectric tunnel junctions, where ferroelectric polarization controls electrical resistance, could improve the performance of these devices.
Sirtuins have been implicated in the ageing process in a variety of organisms, but their role in mammalian ageing remains somewhat controversial. Here the authors discuss sirtuin proteins in the brain, providing an overview of their physiological functions as well as their implication in mammalian ageing.
