Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain
the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in
Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles
and JavaScript.
Atomically disperse catalysts can offer promising activity due to the high exposure of active sites. Here, iridium complexes in solution undergo a binding equilibrium with a nickel oxide surface resulting in atomically disperse iridium and high turnover frequencies for oxygen evolution.
Gastrulation is an early morphogenic event driven by coordinated asymmetric/polarised cell movements. Here, the authors show in zebrafish that Lurap1, a protein that interacts with Dishevelled, regulates Wnt and planar cell polarity, coordinating centriole positioning during convergence and extension.
Parity-time-symmetric optical systems have so far only been realized using microscopic cavities because the necessary gain-loss balance is thought to be fragile with regard to statistical fluctuations. Here, Jahromi et al.. demonstrate PT-symmetric lasing using kilometre-long fibre cavities.
It is well established that odor-evoked excitation in olfactory sensory neurons (OSNs) encodes odor information. Here the authors report that odor-evoked inhibition in OSNs of Drosophila also encodes odor identity, and can in itself drive both attraction and avoidance behaviors.
The neuroectoderm is patterned in a rostral-caudal axis in the embryo but how positional information is interpreted, is unclear. Here, the authors show that in mouse 3D embryonic stem cell cultures, there is self-patterning that depends on sequential activation of localised Fgf then Wnt signalling.
Short telomeres are a hallmark of senescence and can result in genomic instability as well as cancer progression. Here, the authors present TeSLA, a technique to accurately detect telomeres under 1 kb in length.
The disease causing L253P mutation in the actin-binding domain (ABD) of β-III-spectrin drastically increases actin-binding affinity. Here, the authors present the cryo-EM structure of F-actin complexed with the ABD mutant and double electron–electron resonance measurements show how the mutation affects the ABD conformational state.
Devices based on periodic architectures are intrinsically limited in terms of spectral response. Using an interference-based model, the authors design and fabricate plasmonic aperiodic groove array devices which function as light filters and colour sorters with flexible, multi-spectral optical response.
Resolving conflict in an orderly way is beneficial, but it is unclear whether non-human animals make and observe such rules. Here, authors show that mice spontaneously develop and observe such rules, thereby increasing their total, individual reward as well as the reward equity with other mice.
All-optical approaches to modulate signals are of wide interest. Here the authors demonstrate the use of two-dimensional perovskites on silicon for optically controlling the propagation and attenuation of terahertz radiation in the visible by changing the number of atomic layers.
Exosomes are extracellular vesicles that can favor tumor development and metastasis. Here, the authors show that cancer exosomes may also exert a suppressive function; in fact, exosomes from non-metastatic melanoma cells can lead to the recruitment of patrolling monocytes, which clear cancer cells at the pre-metastatic niche.
Understanding the conductivity at the nominally uncharged domain walls in ferroelectrics is still far from complete. Here the authors report an enhanced conduction at domain walls in an ultra-thin (001) BiFeO3 film resulting from the formation of a field-induced meta-stable twisted domain nucleus.
Understanding the dynamics of the skyrmion string lattice is the prerequisite for its potential application as next-generation information carriers. Here, the authors explore the topological unwinding of skyrmion string lattice under the application of current pulses.
Solar eruptions provide opportunities to study magnetic flux ropes, a structure of fundamental importance for both plasma physics and space weather. Here the authors reveal the dynamic formation of a flux rope through its footprint on the solar surface, revealing a highly twisted core structure.
The impacts of top down (precipitation) and bottom-up (groundwater rise) wetting processes on carbon sequestration are poorly understood. Here, the authors use incubation experiments to show that drought legacy and pore-scale wetting patterns are important factors controlling short-term carbon dynamics.
Pancreatic acinar cell carcinoma (ACC) is an aggressive exocrine tumor with largely unknown biology. Here, the authors perform genome- and epigenome-wide analyses from normal and ACC pancreatic tissue that identify aberrations in genome stability and cell cycle control.
Strong regional heterogeneity prevents thorough understanding of the recent increase in Antarctic sea ice. Here, analysis of marine and ice cores in the Western Ross Sea shows that late Holocene contrasting sea ice patterns between open and coastal areas are related to katabatic winds and polynya efficiency.
The tripartite multidrug efflux pump MacA-MacB-TolC in Gram-negative bacterial pathogens is driven by the ATPase MacB, which belongs to the ATP-binding cassette (ABC) superfamily. Here the authors present the 3.4 Å resolution crystal structure of MacB, and compare it with other known ABC transporter structures.
UV-induced mutagenic cyclobutane pyrimidine dimers on nucleosomal DNA are sensed by the damage recognition factors DDB2 and XPC via an unknown mechanism. Here, the authors show that the histone methyltransferase ASH1L regulates the DDB2 to XPC handoff by methylating Lys-4 of histone H3.
The cysteine-rich peptides LUREs play an essential role in pollen tube attraction to the ovule for plant sexual reproduction. Here Zhang et al. show that PRK6 functions as a receptor of the LUREs in Arabidopsis thaliana and reveal the ligand recognition mechanism.