Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain
the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in
Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles
and JavaScript.
In strong field ionization, entanglement between an electron and an ion has been discussed previously. Here the authors explore orbital angular momentum entanglement between the electrons released in non-sequential double ionization.
Changes to structural and functional connectivity can give rise to neurodegeneration and neurodevelopmental diseases. Here the authors investigate molecular and connectomic patterns in 13 different neurological, psychiatric and neurodevelopmental diseases from the ENIGMA consortium.
The ever most widely used eutectic alloys often suffer from limited ductility. Here the authors propose a distinctive concept of phase-selective recrystallization to significantly improve their ductility and strength and pave the way for new applications of the widespread eutectic alloys.
Control of percolative dynamics of metal and insulator domains during electrically triggered insulator-metal transition underlies applications in energy-efficient switches. Jo et al. show that embedded metallic nanoparticles enhance the metastability and memory effects of metallic domains in VO2 switches.
A crystalline hetero-metallic cluster catalyst based on a covalent organic framework strategy is reported. The catalyst can facilitate both photocatalytic oxidative and reductive reactions leading to efficient production of HCOOH from CO2 and H2O.
In obesity, adipose tissue is chronically inflamed, leading to insulin resistance, and adipose tissue macrophages (ATMs) are a major source of cytokines that aggravate adipocyte dysfunction. Here, the authors show that selective deletion of the epidermal growth factor receptor in ATMs decreased obesity and development of insulin resistance.
New study defines key guidelines to accurately assess the alignment of companies with Paris goals, finding that current methods to evaluate performance are deficient with few companies assessed as Paris Compliant.
The synthesis and characterization of new crystalline-amorphous hybrid materials is challenging. Here, the authors report the preparation of a nested order-disorder framework by applying high pressure to a nested copper chalcogenide Cu12Sb4S13.
Magnetohydrodynamic instabilities are related to different characteristics and behavior of fluids. Here the authors report an experiment and simulation combined study of a global non-axisymmetric MHD instability that exists at sufficiently large rotation rates and intermediate magnetic field strengths.
Difficulty with purification, structural heterogenicity, and limited water solubility of β-glucans has significantly limited their therapeutic applications. Here, the authors report the synthesis of (1→6)-β-glucose-branched poly-amido-saccharides as glycan-mimetics and demonstrate macrophage stimulation and polarization.
Marine protected areas are proposed to protect elasmobranchs (sharks, skates, and rays) but the fishing impact from small-scale fisheries in these areas is unknown. From 1256 fishing operations carried out in partially protected and unprotected areas in six Mediterranean countries, this study shows that catches were higher in partially protected areas than in unprotected areas, indicating poor small-scale fisheries management as a threat for these species.
Karalis et al show that genetic reduction of the mTORC1 component Raptor improves multiple phenotypes in mouse models of TSC. Their findings suggest that Raptor could be a potential therapeutic target for treating the neurological aspects of TSC.
Hyperinflammation and immune dysfunction are key drivers of immunopathology in sepsis. Here the authors show microbial exploitation of phagocytic receptors is linked to triggering of sepsis and the immune cell mediated reduction in neutrophil life span.
The authors revealed novel roles of catalytic residues and divalent metal ions for hsTOP3B, the human RNA topoisomerase, and demonstrated the structural elements that kinetically modulate the DNA and RNA topoisomerase activities of TOP3B.
Capacitive soft force sensors require electrical shielding from electromagnetic interference, but this shielding can mess with the effectiveness of the sensing electrodes. Here, Aksoy et al. solve this problem by patterning the central sensing elastomer layer to control its compressibility.
In quantum computing, realistic error models can allow tailored correction schemes for specific platforms. Here, while considering the case of qubits encoded in metastable electronic levels of atomic arrays, the authors propose a way to convert a large fraction of occurring errors into detectable leakages, or erasure errors, which are vastly easier to correct.
Coronaviruses may spill over from bats to humans. This study uses epidemiological data, species distribution models, and probabilistic risk assessment to map overlap among people and SARSr-CoV bat hosts and estimate how many people are infected with bat-origin SARSr-CoVs in Southeast Asia annually.
We show cryovolcanic eruptions released sufficient methane to source volatile products on Charon. Irradiated methane products are found on other Kuiper belt objects, so endogenically sourced volatiles could be important across the Kuiper belt.
Work in a mouse model of Friedreich’s ataxia has shown that administration of the cytokine granulocyte-colony stimulating factor (G-CSF) could have beneficial neuroprotective effects. Here the authors perform a pilot study of Lenograstim (recombinant G-CSF) in patients with Friedreich’s ataxia.
There are only a few platforms that integrate multiple omics data types, bioinformatics tools, and interfaces for integrative analyses and visualization that do not require programming skills. Here the authors present an integrative web-based platform for analysis of omics data and signatures of cellular perturbations.