Articles

Mutations in the DNA helicaseBLM cause Bloom syndrome, which is characterized by slow replication fork progression and genetic instability. Here, cells lacking BLMare shown to have a defect in cytidine deaminase, which alters the pyrimidine pool and results in replication fork progression with altered velocity.

Nitric oxide can be produced by nitric oxide synthase or by nitrite reduction, but whether the latter occurs inside cells is unknown. Here, the TRPV3 ion channel is shown to induce nitrite-dependent nitric oxide production in keratinocytes, where it has a role in thermosensory behaviour and wound healing.

TRF1 is a telomere binding protein involved in sister telomere cohesion. In this study, the ability of TRF1 to bind to telomeres in mitosis is inhibited by cyclin-dependent kinase 1-mediated phosphorylation, which may facilitate sister telomere resolution during mitosis.

Anyons are particles with fractional statistics that interpolate between bosons and fermions, and are thought to exist in low-dimensional systems. Keilmannet al. propose an experimental system to create anyons in one-dimensional optical lattices using assisted Raman tunnelling.

A bubble at an air–liquid interface can form a liquid jet upon bursting, spraying aerosol droplets into the air. Leeet al. show that jetting is analogous to pinching-off in liquid coalescence, which may be useful in applications that prevent jet formation and in the improved incorporation of aerosols in climate models.

Waveplates are used in optoelectronics to alter the polarization of light, but they do not typically perform achromatically, which is important for applications such as three-dimensional displays. Here, biologically inspired periodically multilayered structures are produced, which function as achromatic visible-light waveplates.

In animals, cryptochrome proteins are thought to be the detectors of the Earth's magnetic field, but humans have not been shown to posess mangetosensing capabilities. Foleyet al. demonstrate that the human cryptochrome protein, CRY2, when expressed in Drosophila melanogastercan mediate magnetoreception in a light-dependent manner.

Light–matter interactions can be used to manipulate magnetization in solids, but light-controlled magnetization vector motion has not been demonstrated. Here, two-dimensional magnetic oscillations in NiO are manipulated with optical pulses leading to vectorial control of magnetization by light.

Optoelectronic devices such as conventional semiconductor lasers are used to study the chaotic behaviour of nonlinear systems. Here chaos is observed for quantum-dot microlasers operating close to the quantum limit with potential for new directions in the study of chaos in quantum systems.

The vomeronasal organ detects pheromones, which are thought to activate TRPC2 channels on the surface of vomeronasal neurons. Using TRPC2 knockout mice, the authors show that urinary pheromones can also activate these neurons via calcium-activated chloride channels, suggesting a TRPC2-independent pathway for sensing pheromones.

Single nanoparticles are known to emit light intermittently, or 'blink', but the mechanisms describing this phenomenon are not fully understood. This study demonstrates that, for small clusters of blinking nanoparticles, the number of particles within a cluster dramatically influences blinking time.

Anodes composed of nickel/yttria-stabilized zirconia in solid oxide fuel cells are known to suffer from coking, which reduces their performance. Here, Yang and colleagues report a new barium oxide/nickel anode, which efficiently oxidizes fuel with minimum carbon buildup.

Cell division and cilium formation are dependent on centrosomes that consist of two centrioles and pericentriolar material (PCM). In this study, the Sas-4 protein is shown to be important in mediating the formation of cytoplasmic PCM complexes and the incorporation of this material into centrosomes.

Cyanide, a known plant defence compound, can also stimulate seed germination. Flemattiet al. show that glyceronitrile is produced in wildfire smoke, which can release cyanide and stimulate seed germination of fire-responsive plant species, thus serving as an ecological store of cyanide.

The sensitivity of human populations to rising global temperatures is not yet fully understood. The authors describe the link between temperature and daily mortality in over 200 European regions and calculate projections of mortality from climate models under greenhouse gas scenario simulations.

Acoustic communication is important for the reproductive behaviour of frogs. Using acoustic playback experiments, Shenet al. show that calls from male concave-eared frogs (Odorrana tormota) evoke vocal responses and phonotaxis from females, but the females show no ultrasonic sensitivity.

SiO₂ glass and helium are important in various fields of science and engineering. Sato et al. show SiO₂glass to be less compressible in helium under high pressure, which may be relevant for the interpretation of high-pressure experiments and in the design of new materials.

Negative thermal expansion—contraction upon heating—is an unusual process that may be exploited to produce materials with zero or other controlled thermal expansion values. Azumaet al. observe negative thermal expansion in BiNiO₃which is a result of Bi/Ni charge-transfer transitions.

A quantum key distribution system allows two remote parties to communicate in secret by a shared key code. This work demonstrates a complete and undetected eavesdropping attack on a quantum key distribution connection, highlighting the need for further security updates on secure communication systems.

In this study, a bacterium is identified in the honeydew of aphids, which produces volatile chemicals and attracts hoverflies. The findings could aid the development of pest control systems for aphids.