Browse Articles

Coherently interfacing microwave and optical radiation at the single photon level is an outstanding challenge in quantum technologies. Here, the authors show bi-directional on-chip conversion between MW and optical frequencies exploiting piezoelectric actuation of a gallium phosphide optomechanical resonator.

Here, via applying metagenomics and metabolomics analyses, the authors show that fecal microbiota composition and microbiota-derived metabolites predict the trajectory of respiratory function and death in patients with severe SARS-Cov-2 infection, suggesting the gut-lung axis to play an important role in the recovery from COVID-19.

This study finds that projections of future extreme precipitation can be made more reliable using a constraint from observed present-day precipitation variability, which reduces projection uncertainty by 20–40% over the extra-tropics.

While the combination of synthetic and biological systems offers an appealing strategy for solar-to-fuel conversion, such hybrid systems typically suffer from low selectivity. Here, authors integrate a bimetallic alloy with a CdS-containing methanogen for selective CO₂ reduction to methane.

Spaulding et al. survey RG/RGG repeats in C. elegans and identify the homologs of Nucleolin (NUCL-1) and GAR1 (GARR-1). RG/RGG repeats are dispensable for nucleolar accumulation but critical for sub-nucleolar phase separation.

How functional connectivity gradients in the cortex arise and vary dynamically is not fully understood. Here the authors show that gradients are determined by structural wiring but may be modulated by arousal levels.

Van der Waals materials are characterized by two dimensional layers weakly held together by interlayer van der Waals forces. Here, the authors study how shear motions between these layers influence the magnetic properties of the van der Waals antiferromagnets FePS3, MnPS3, and NiPS3. ‘

The optoelectronic performance of lead halide perovskite in highfluence applications are hindered by heterogeneous multi-polaron interactions in the nanoscale. Here, Nishda et al. spatially resolve sub-ns relaxation dynamics on the nanometer scale by ultrafast infrared pumpprobe nanoimaging.

A challenge in synthetic biology is the empirical characterisation of genetic parts. Here the authors present FPCountR, a validated method and accompanying R package that enables the precise quantification of fluorescent protein reporters per bacterial cell to be enumerated in ‘proteins per cell’ or nanomolar units without requiring protein purification.

von Willebrand factor (VWF) plays a critical role in primary hemostasis following vascular injury by tethering platelets to exposed collagen. Here, VWF binding to macrophages is shown to trigger NF-κB activation and induce pro-inflammatory responses.

Flexible magnetic sensors with high sensitivity have a wide variety of medical and industrial uses, however, making such sensors robust and flexible at the same time can be challenging. Here, the authors demonstrate a high sensitivity flexible magnetic sensor that exhibits self-healing under an applied alternative magnetic field, with complete performance recovery.

Cytoplasmic accumulation of RNA binding protein, hnRNPK in cancer cells is associated with poor prognosis. Here the authors show that SCF^Fbxo4 E3 ubiquitin ligase-mediated polyubiquitylation of hnRNPK restricts c-Myc translation and limits cancer progression.

RNA velocity can detect the differentiation directionality by modelling sparse unspliced RNAs, but suffers from high estimation errors. Here, the authors develop a computational method called UniTVelo to reinforce the velocity estimation by introducing a unified time and a top-down model design.

Rodent sensory cortex contains intermixed representations of sensory features. Here the authors investigated the whisker somatotopic map among L2/3 pyramidal neurons in somatosensory cortex in awake mice performing a sensory discrimination task.

The separation of sensor, memory, and processor in a recognition system deteriorates the latency of decision-making and increases the overall computing power. Here, Zhang et al. develop a photoelectronic reservoir computing system, consisting of DUV photo-synapses and a memristor array, to detect and recognize the latent fingerprint with in-sensor and parallel in-memory computing.

JAK2V617F mutation is associated with an increased risk for athero-thrombotic cardiovascular disease, but its role in aortic disease development remains unknown. Here, the authors show that JAK2V617F mutation drives vascular resident macrophages toward a pathogenic phenotype and promotes dissecting aortic aneurysm.

Analysis of the protein corona formed around nanoparticles is important for multiple applications in nanomedicine, the methods used at core facilities used for analysis can impact the results. Here, the authors report on a study into the variability of the results obtained from 17 different core facilities and the implications of this.

The authors present a subcutaneous power supply which coverts NIR-II light to electricity via combination of photothermal conversion and thermoelectric conversion. They demonstrate that it can recharge an implanted wireless camera upon irradiation with NIR-II light through the skin.

In strongly correlated materials multiple electronic phases can form simultaneously in real space, offering the potential of devices with multiple electronic properties, if such phase separation can be controlled. Here, Li et al study this electronic phase separation in LaMnO3/CaMnO3/PrMnO3 superlattice, and find a nano-network electronic phase separation resulting from local strain relaxation that persists through thermal cycling.

Motile and non-motile cilia have distinct functions and protein complexes associated with them. Here, the authors show the conserved protein CFAP20 is important for both motile and non-motile cilia and is distinct from other ciliopathy-associated domains or macromolecular complexes.