Browse Articles

The stabilization of low-coordinate boron radicals is challenging, as they tend to form strong chemical bonds. Here the authors report the isolation and structural characterization of a dicoordinate boron radical featuring a π-donating amino and a π-accepting carbene ligand.

Monitoring the aging process in vivo is challenging. Here the authors generate a Glb1^+/m‒Glb1-2A-mCherry (GAC) reporter mouse model, where the GAC signal is consistently correlated with established biomarkers of cellular senescence, cardiac hypertrophy and shortened lifespan, which may prove helpful for studies developing anti-aging interventions.

Here, the authors use reproductive mode data with matching phylogenetic data to explore the evolution of reproductive mode, transitions between reproductive modes, and diversification rates in amphibians.

Designing efficient reconfigurable field effect transistors remains a challenge. Here, the authors develop a transistor with three distinct operation modes, realized directly on an industrial 22nm FDSOI platform, demonstrating a reconfigurable analog circuit element with signal follower, phase shifter, and frequency doubler operation.

In this study, the microbiota of multiple body sites from 101 marine fish species from Southern California were sampled and analysed. The authors compared diversity measures while also establishing a method to estimate microbial biomass. Body site is shown to be the strongest driver of microbial diversity and patterns of phylosymbiosis are observed across the gill, skin and hindgut.

Systemic risk and bank bailout approaches have been the source of discussions on scientific, financial and governmental forums. An artificial intelligence technique is proposed to inform equitable bailout decisions that minimise taxpayers’ losses.

Here, the authors report the cryoEM structure of AA amyloid from a cat shelter with extreme disease prevalence and reveal the feline-specific sequence insert in the fibril core. The sequence is 99% identical to AA amyloid from cheetah with reported prion-like transmission in zoos.

Rigorous, robust replication and generalization studies present a significant investment into the quality of the research record, the foundation on which new research is built. Communications Psychology and the Human Behaviour Team at Nature Communications are inviting submissions of replication studies in psychology and the human behavioural sciences.

The Su-Schrieffer-Heeger (SSH) model is a prototypical model of topological states, initially proposed to describe spinless electrons on a one-dimensional (1D) dimerized lattice. Here, the authors realize a 2D SSH model in a rectangular lattice of silicon atoms on a silver substrate, observing gapped Dirac cones by angle-resolved photoemission spectroscopy.

Growing evidence indicates that YAP/TAZ transcriptional regulators promote autophagy. Here, the authors characterize the role of YAP against Staphyloccocus aureus infection of synovial organoids and describe the role staphylococcal toxins have in antagonizing YAP-mediated functions.

Liposomes are widely used in pharmaceuticals yet trade-offs between uniform size and mass production, limit production and application. Here, the authors report on the design of a microfluidic vortex focusing microfluidic technique which can mass produce liposomes with controlled size and low variability.

The lanthanum-hydrogen system has attracted attention following the observation of superconductivity in LaH₁₀ at near-ambient temperatures and high pressures. Here authors describe the high-pressure syntheses of seven La-H phases; they report crystal structures and remarkable regularities in rare-earth element hydrides.

Land use intensification could make soil food webs less able to recover from drought. Here, the authors find that intensive grassland management impairs recent photosynthate flux to roots and soil biota after drought, whereas extensive grassland management buffers the legacy of drought.

Plasmodium kinesin-8B is essential for male gamete formation and its absence blocks parasite transmission. Using cryo-EM and TIRF, the authors report how kinesin-8B motor domains are tuned to support microtubule motility and depolymerase activity.

While the impact of F-actin architecture on stress transmission is well studied, the role of architecture on stress generation remains unclear. Here authors use in vitro model and show that distinct organizations constrain myosin motion.

In this study, the authors provide a global overview of SARS-CoV-2 genome sequencing, and estimate the proportion of cases sequenced and time to genome upload. They identify disparities and highlight the need to strengthen surveillance in lower and middle income countries.

IL-6 and RasGRP1 have been shown to have important functions during inflammation and cancer. Here the authors propose the protein and mRNA of RasGRP1 have opposing functions by promoting IL-6 mediated acute inflammation and inhibiting inflammation-associated cancer through mRNA and protein mechanisms respectively.

Developing highly efficient catalysts for selective oxidation of benzene to phenol with low H₂O₂ consumption remains challenging. Here the authors report a highly active and selective non-noble metal catalyst for selective oxidation of benzene to phenol with low H2O2 addition via regulating the electron configuration of single-atom Cu catalyst.

Synaptic connections are critical for brain function but are hard to measure systematically. Here, authors present a method which uses rabies virus barcoding and single-cell RNAseq to parallelize monosynaptic network reconstruction from molecularly-profiled single cells.