Browse Articles

Filter By:

  • In microscopy, the standard quantum limit represents the best achievable signal-to-noise ratio for a given light intensity. Here, the authors build an optical microscope that uses entanglement between photon pairs to overcome this barrier.

    • Takafumi Ono
    • Ryo Okamoto
    • Shigeki Takeuchi
    Article
  • Methane is a major constituent of planetary interiors, yet phase relations in the C–H system are poorly understood. This work documents the chemical reactivity of the C–H system over a wide range of temperatures and pressures, and sheds light on the chemical composition of Earth and icy giants.

    • Sergey S. Lobanov
    • Pei-Nan Chen
    • Alexander F. Goncharov
    Article
  • Transport of DNA molecules across lipid membranes requires protein conduits such as the nuclear pore complex. Franceschiniet al.engineer an artificial sequence-selective DNA transporter by attaching gating oligonucleotides to a bacterial nanopore.

    • Lorenzo Franceschini
    • Misha Soskine
    • Giovanni Maglia
    ArticleOpen Access
  • Mutually exclusive splicing of genes is a mechanism for generating proteome diversity. Here Kollmar et al. determine the mutually exclusive spliced exome of Drosophila melanogaster and reveal insights into its evolutionary history within the Drosophilagroup.

    • Klas Hatje
    • Martin Kollmar
    Article
  • The mechanical properties of brittle materials are largely determined by how cracks propagate through them. Contrary to expectations, Kermodeet al.show that a crack propagating below a critical speed through a silicon crystal can be scattered by a single isolated boron impurity.

    • J.R. Kermode
    • L. Ben-Bashat
    • A. De Vita
    Article
  • Although it has been possible to calculate the conditions for exerting complete control over a directed complex network, for undirected and weighted networks this calculation is inexact. Yuan et al. develop a general framework for determining the controllability of any complex network.

    • Zhengzhong Yuan
    • Chen Zhao
    • Ying-Cheng Lai
    ArticleOpen Access
  • Colorimetric differentiation of solvents is difficult as many solvatochromic molecules exhibit broad overlaps in their absorption and emission bands. Here, the authors present a ‘turn-on’ type sensor in which the colorimetric sensor responds only when its protective layer is disrupted by a specific solvent.

    • Jung Lee
    • Hyun Taek Chang
    • Jong-Man Kim
    ArticleOpen Access
  • The coherence time describes the timescale over which particles can still display wave-like interference and is important for quantum optics. Using multi-photon interference experiments, Ra et al. show that the multi-photon coherence time depends on both the number of photons and the detection scheme used.

    • Young-Sik Ra
    • Malte C. Tichy
    • Yoon-Ho Kim
    Article
  • Prion protein has been suggested to bind toxic amyloid-ß oligomers. Nicollet al.demonstrate that binding to prion protein and prion protein-dependent synaptotoxicity correlate with the presence of a tubular form of amyloid-ß with a defined triple helical structure.

    • Andrew J. Nicoll
    • Silvia Panico
    • John Collinge
    ArticleOpen Access
  • Mouse models of influenza infection that permit monitoring of infection in living animals are scarce. Here Pan et al. describe an engineered influenza virus expressing luciferase, which enables real-time in vivovisualization of viral infection and assessment of antiviral drugs.

    • Weiqi Pan
    • Zhenyuan Dong
    • Ling Chen
    ArticleOpen Access
  • Hyperpolarization of chemical nuclei is known to greatly increase sensitivity to characterization by magnetic resonance imaging. Here a new platform that allows for the design of a number of hyperpolarized probes for chemical sensing applications is demonstrated.

    • Hiroshi Nonaka
    • Ryunosuke Hata
    • Shinsuke Sando
    ArticleOpen Access