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Measuring the entanglement between down-converted photons is central to many quantum optical experiments, and is normally performed by scanning detectors stepwise across a plane. Edgaret al. use a CCD camera to measure the entire entangled light field, finding strong correlations in position and momentum.
Coherent diffractive imaging exploits coherent X-ray sources to image objects from their diffraction patterns, but fails for decreasing coherence. Using partially coherent diffraction patterns, Clarket al. obtain three dimensional reconstructions of nanocrystals and determine the wavefield coherence.
Quantum spin ice is a magnetic state of matter which can play host to monopole excitations. Using polarized neutron scattering, Changet al. show that the quantum spin ice material ytterbium titanate undergoes a Higgs transition of emergent magnetic monopoles from a Coulomb liquid to a ferromagnetic phase.
Changes in gene expression in the hippocampus and the cortex are pivotal for memory consolidation. Gräff and colleagues use a recognition task in mice to show that epigenetic post-translational modifications are rapidly activated in the hippocampus after learning, but induced with a delay in the cortex.
The bacterial channel protein MscL opens in response to mechanical forces and could be exploited for vesicular-based drug delivery. Doerneret al. show that functional MscL can be expressed in mammalian cells and facilitate the controlled cellular uptake of relatively large, membrane-impermeable bioactive molecules.
Following retinalcis/trans isomerisation, the active form of the G-protein-coupled receptor rhodopsin decays to opsin and all-trans-retinal. In this study, arrestin, a regulator of G-protein-coupled receptor activity, is shown to facilitate the concurrent sequestering of toxic all-trans-retinal and regeneration of 11-cis-retinal within the opsin population.
The role of CD4+ T cells in the generation of memory CD8+ T cells is not fully understood. In this study, the exposure of CD8 memory precursors to interleukin-2 during early antigen priming is shown to be controlled by FoxP3+ regulatory CD4+T cells, resulting in the production of functional memory cells.
Non-uniform light beams can create patterns in azo-polymer films by inducing mass transport, yet the process is not well understood. Using optical vortex beams, Ambrosioet al. observe the formation of spiral patterns that are surprisingly sensitive to the optical phase, which they explain with a new model.
It is unclear where in the nucleus splicing takes place and how much occurs post-transcriptionally. Using antibodies raised against a phosphorylated splicing factor, Girardet al. show that the majority of splicing occurs co-transcriptionally and that post-transcriptional splicing occurs in nuclear speckles.
Vortex states in magnetic nanoislands are characterized by a curling of the magnetization in the plane of the disk. This study demonstrates experimentally that vortices tend to form with a preferred handedness that is dictated by the Dzyaloshinskii–Moriya interaction.
Light-matter interactions are generally dominated by electric fields and electric-dipole transitions. This study, however, quantifies magnetic contributions to light emission and so exploits the strong natural magnetic-dipole transitions in lanthanide ions to measure optical-frequency magnetic fields.
Topologically protected states of matter are receiving widespread attention owing to their unusual electronic properties. Using numerical simulations, this study predicts that tin telluride is a physical realization of a new class of materials termed topological crystalline insulators.
The Kondo coupling causes electron mass enhancement in rare earth materials, but not in otherd electron systems. Shimizu et al. report on the combination of frustrated spin liquid and strong Hund's coupling in a vanadium spinel as a mechanism for the microscopic origin of heavy dfermions in transition metals.
The integration of flexible electronics with conventional devices has been hampered by the lack of suitable soldering techniques able to withstand stretching. Jeonget al. use a porous substrate to fabricate biocompatible, stretchable electronics that can be interfaced with commercial components.
Fbw7 is a ubiquitin-ligase, which targets several oncoproteins for proteolysis, and is therefore important for the control and prevention of tumorigenesis. In this study, Arabi and colleagues carry out a proteomic screen of the targets of Fbw7, and identify Nuclear Factor of κ-B2 as a substrate.
Fas-associated protein with death domain (FADD) is part of a signalling complex that controls some forms of programmed cell death. Lee and colleagues demonstrate that FADD ubiquitination by the E3 ubiquitin ligase MKRN1 regulates FADD protein stability and thereby cell death.
Whether humans are the only animals with cultural behaviour remains an open question in behavioural research. Here, a network analysis of the social preferences among bottlenose dolphins in Shark Bay, Australia finds that tool-using dolphins prefer others like themselves, suggesting the presence of cultural behaviour.
The peptide sequence of transcription activator-like effectors (TALEs) can be customized to tailor the binding of TALEs to specific DNA sequences. Conget al. improve TALE specificity for guanine binding and use a genetic construct based on TALEs to efficiently repress expression of a target gene.
Nacre is an organic–inorganic composite biomaterial, which consists of an ordered multilayer structure of crystalline calcium carbonate platelets separated by porous organic layers. Finnemoreet al. present a route to artificial nacre which mimics the natural layer-by-layer biosynthesis.
Patchy colloids are colloidal particles with chemically or physically patterned surfaces that result in complex interactions arising between them. By means of numerical simulations, Romano and Sciortino show that suitably tailored patches can induce the crystallization of patchy colloids into specific crystal structures.