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Latest research

  • Complex interatomic interactions and diverse structures make computing the phase diagram of water very challenging. Here, a combination of machine learning and advanced free-energy methods at three levels of hybrid DFT enables the prediction of the phase diagram in close agreement with experiment.

    • Aleks Reinhardt
    • Bingqing Cheng
    Article Open Access
  • Goto et al present a bolometer based around the heat generation in magnetic tunnel junctions under auto-oscillation conditions. Unlike superconducting bolometers, the presented device operates at room temperature and sub-GHz frequencies, opening possibilities for use in microwave devices.

    • Minori Goto
    • Yuma Yamada
    • Yoshishige Suzuki
    Article Open Access

Subjects within Physical sciences

  • The regulation of aircraft engine NOx emissions was introduced to improve local air quality and reduce NOx emissions at altitude. Here, the authors find that greater fuel efficiency of aircrafts, and therefore lower CO2 emissions, could be preferable to reducing NOx emissions in terms of the aviation industries future climate impacts.

    • Agnieszka Skowron
    • David S. Lee
    • Bethan Owen
    Article Open Access
  • Melting of the Greenland Ice Sheet—a threat for sea level rise—is accelerated by ice algal blooms. Here the authors find a link between mineral phosphorus and glacier algae, indicating that dust-derived nutrients aid bloom development, thereby impacting ice sheet melting.

    • Jenine McCutcheon
    • Stefanie Lutz
    • Liane G. Benning
    Article Open Access
  • Forest structure depends both on extrinsic factors such as climate and on intrinsic properties such as community composition and diversity. Here, the authors use a dataset of stand structural complexity based on LiDAR measurements to build a global map of structural complexity for primary forests, and find that precipitation variables best explain global patterns of forest structural complexity.

    • Martin Ehbrecht
    • Dominik Seidel
    • Christian Ammer
    Article Open Access
  • Globally, new particle formation represents a major source of cloud condensation nuclei. Here, the authors present evidence of frequent occurrence of new particle formation in the upper part of remote marine boundary layer following cold front passages.

    • Guangjie Zheng
    • Yang Wang
    • Jian Wang
    Article Open Access

Subjects within Earth and environmental sciences

  • Pyruvate kinase phosphorylates histone H3T11 (H3pT11) and represses gene expression by forming a large complex SESAME (Serine-responsive SAM-containing Metabolic Enzyme). Here the authors show that SESAME-catalyzed H3pT11 regulates telomere silencing by promoting Sir2 binding at telomeres and preventing autophagy-mediated Sir2 degradation.

    • Shihao Zhang
    • Xilan Yu
    • Shanshan Li
    Article Open Access
  • The trajectory of the emergence of Zika virus (ZIKV) into the Americas remains unclear. Here, the authors find that four mutations originated before ZIKV introduction to the Americas are direct reversions of previous mutations that accompanied spread many decades ago from ZIKV’s native Africa to Asia, and show in experimental infections of mosquitoes, human cells, and mice that the original mutations reduced fitness for urban transmission, while the reversions restored fitness, likely increasing epidemic risk.

    • Jianying Liu
    • Yang Liu
    • Scott C. Weaver
    Article Open Access
  • Synthetic biologists often co-opt heterologous parts to affect new functions in living cells, yet such an approach has rarely been extended to structural components of the ribosome. Here, the authors describe generalizable methods to express ribosomes from divergent microbes in E. coli and maximize their function.

    • Natalie S. Kolber
    • Ranan Fattal
    • Ahmed H. Badran
    Article Open Access
  • The BLM helicase interacts with the topoisomerase TOP3A and RMI1 to form the BTR complex. Here, the authors reveal that this complex contains multiple binding sites for the single-stranded DNA-binding complex RPA, and that RPA-binding stimulates BLM recruitment to stalled replication forks to promote their restart after replication stress.

    • Ann-Marie K. Shorrocks
    • Samuel E. Jones
    • Andrew N. Blackford
    Article Open Access

Subjects within Biological sciences

Subjects within Health sciences

  • Writing in Nature communications, Zhu and collaborators reported the development of a genetically encoded sensor for the detection of formaldehyde in cells and tissues. This tool has great potential to transform formaldehyde research; illuminating a cellular metabolite that has remained elusive in live structures.

    • Carla Umansky
    • Agustín E. Morellato
    • Lucas B. Pontel
    Comment Open Access
  • Many newly-discovered microbial phyla have been studied solely by cultivation-independent techniques such as metagenomics. Much of their biology thus remains elusive, because the organisms have not yet been isolated and grown in the lab. Katayama et al. lift the curtain on some intriguing biology by cultivating and studying bacteria from the elusive OP9 phylum (Atribacterota).

    • Muriel C. F. van Teeseling
    • Christian Jogler
    Comment Open Access
  • The publication of a paper on mentorship, now retracted, led us to reflect on our editorial processes and strengthened our determination in supporting diversity, equity and inclusion in research.

    Editorial Open Access
  • Dr Nicolas Mano is a Senior Researcher at Centre de Recherche Paul Pascal, France. His research interests include (bio)electrochemistry, biosensors, biofuel cells, enzymes engineering, and the use of carbonaceous materials for electrodes. His aim is to develop approaches where biochemical fuels can be converted into electricity and applied into bioelectrochemical applications. In this conversation, he is discussing the advancements in the field of biofuel cells in the past ten years and look ahead at future developments.

    Q&A Open Access
  • It would be unwise to assume ‘conventional’ lithium-ion batteries are approaching the end of their era and so we discuss current strategies to improve the current and next generation systems, where a holistic approach will be needed to unlock higher energy density while also maintaining lifetime and safety. We end by briefly reviewing areas where fundamental science advances will be needed to enable revolutionary new battery systems.

    • Clare P. Grey
    • David S. Hall
    Comment Open Access
Organic chemistry and chemical biology

Organic chemistry and chemical biology

This page provides a snapshot of some of the most exciting work published in the areas of organic chemistry, chemical biology, polymers and hydrogels as well as biomaterials and functional organic materials, and chemical soft matter.
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