Ultrasound-driven bioelectronics offer a wireless scheme for implants. Here, the authors reported a lead-free dual-frequency ultrasound implants for wireless, biphasic deep brain stimulation.

Utilizing “Chemistry at a point”, Ni is exsolved from a perovskite lattice under deposited Pt nanoparticles. This yields even smaller Ni Pt alloy nanoparticles on a perovskite nanofiber structure, exhibiting high catalytic activity.

The preparation of atom-thick lattices with Å-scale pores is desirable for achieving ion selectivity and high ion flux. Here authors present a cm-scale membrane made of atom-thick graphene film hosting zero-dimensional pores spanning only a few Å, repaired using an in situ electrochemical strategy, yielding high Li⁺/Mg²⁺ separation performance.

Understanding the role of coherent structures in the dynamics of turbulent flows is of high relevance for fluid dynamics, climate systems, and aerodynamics. The authors propose a deep learning approach to evaluate the importance of various types of coherent structure in the flow, to uncover main mechanisms of wall-bounded turbulence and develop techniques for its control.

Here, the authors demonstrate a wafer-scale, low-temperature process using atomic layer deposition, for the synthesis of uniform, conformal amorphous boron nitride (aBN) thin films. They further fabricate aBN-encapsulated monolayer MoS₂ field-effect transistors.

The authors find an unprecedented human-induced weakening of the Northern Hemisphere Hadley circulation in recent and coming decades, contrasting with the naturally-forced simulated strengthening over the preindustrial last millennium.

Cities that experience compact development tend to witness more extreme rainfall over downtown than their rural surroundings, while the anomalies in extreme rainfall frequency diminish for cities with dispersed development patterns.

The sources and sinks of Re and U in the modern ocean may be imbalanced, according to sedimentary porewater analysis and assessment of reductive Re and U removal on the continental shelf

Australian estuaries shown to emit more CO₂ per unit area than global estuaries due to the dominance of macrotidal subtropical and tropical tidal systems, while disturbance effects were minimal due to low overall disturbance.

The authors reveal a 3.9% intensification in the sea surface temperature seasonal cycle over the past four decades, with hotspot regions experiencing intensification of up to 10%. This intensification extends throughout the mixed layer, amplifying the seasonal cycle of upper-ocean oxygenation.

Microfibrillar-associated protein 4 (MFAP4) is involved in fibrotic and cardiovascular diseases. Wozny et al. reveal structural aspects mediating MFAP4 octamer formation critical for its interaction with elastogenic proteins and cells.

Here, the authors utilise NMR and cryo-EM to characterise the binding of an allosteric modulator to μ-opioid receptor (MOR), revealing modulator binding can potentiate receptor activation by altering the conformational dynamics in the core region of MOR.

In this work, the authors apply polymer models to reconstruct the 3D structure of the genome during SARS-CoV-2 infection and examine how the virus impacts key mechanisms of chromatin organization.

The uniformity of laminar processing in a cortex remains not fully understood. Here authors show that high spatial frequency stimuli elicit distinct active patterns across V1 layers, arising from multiple mechanisms involving M and P pathways.

Here, the authors provide structural and biochemical data describing the mechanism through which cGAS synthesizes 2′−5′/3′−5′-cGAMP.

The main challenge for anti-HSV therapy is to target latent virus in ganglionic neurons. Here, the authors report a well-tolerated anti-HSV gene editing approach against HSV which targets latent HSV genomes and leads to reductions of ganglionic viral loads, and viral shedding upon reactivation in mouse models.

As demand for organ transplants exceeds availability there has been an unmet need to extend preservation of deceased donor kidneys. Here, the authors show that a cell-free nutrient-supplemented perfusate allows 4-day preservation of human kidneys using spatially resolved lipidomics and metabolomics.

Current thyroid ultrasounds rely heavily on the experience and skills of the sonographer and of the radiologist, and the process is physically and cognitively exhausting. Here, the authors show a fully autonomous robotic ultrasound system, which is able to scan thyroid regions without human assistance and identify malignant nodules.

High levels of extended spectrum beta-lactamase (ESBL) and carbapenemase encoding genes were detected in bacterial isolates causing neonatal sepsis in LMICs. Authors assess the in vitro activity of three antibiotics (fosfomycin, flomoxef and amikacin) in combination against ESBL-producing Klebsiella pneumoniae and Escherichia coli isolates.

Cardiovascular events are the main cause of mortality in patients with metabolic dysfunctionassociated steatohepatitis (MASH). Here, the authors show that lanifibranor improves cardiometabolic health - insulin sensitivity, lipid and glucose metabolism, systemic inflammation and hepatic steatosis.

Cities that experience compact development tend to witness more extreme rainfall over downtown than their rural surroundings, while the anomalies in extreme rainfall frequency diminish for cities with dispersed development patterns.

Human groups preserve cultural history in songs passed between generations. Here the authors show that musical histories are largely independent of the history preserved in genes and languages.

Incorporating spin crossover motifs into mechanically interlocked molecules offers various switchable properties. Here, the authors report two Fe^II catenated metal-organic frameworks that exhibit spin dependent luminescence and dielectric switching.

Assumptions about the use of biomass and CO₂ sequestration drive key differences in how emissions from remaining fuels are mitigated in net-zero energy systems, with potentially significant tradeoffs that will need to be evaluated and managed.

Plastics, chemical production, and fertilizers commonly rely on fossil fuels. Here the authors examine these uses in China and find that in 2017, 5%, 15%, and 7% of China’s total coal, crude oil, and natural gas were used as feedstocks in the chemical industry.