Nanometer thin membranes filtering boron and phosphorus from water

Microporous organic nanotube assisted design of high performance nanofiltration membranes

Based on the design of natural, porous organic nanotubes, Shuangqiao Han et al. fabricate 15 nm thin membranes that can be used for water purification, specifically to filter out boron and phosporus. 

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  • To elucidate the relationship between sociality and longevity, the authors perform phylogenetic and transcriptomic comparative analysis of mammals. They find that group-living species lived longer than solitary species and identify 31 genes, hormones, and immunity-related pathways involved in this connection.

    • Pingfen Zhu
    • Weiqiang Liu
    • Xuming Zhou
    Article Open Access
  • Here, using a mouse model, the authors report a previously undescribed role for medium-chain acyl-CoA dehydrogenase in host metabolism of gut microbiota metabolites, and show that circulating compounds, including the abundant organic acid hippurate, depend on host-microbe co-metabolism of phenylalanine by Clostridium sporogenes.

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    • Haoqing Chen
    • Dylan Dodd
    Article Open Access
  • ‘Manufacturing CAR-T cells is a streamlined and highly regulated procedure involving T-cell-expansion and activation on a standardised platform. Here, the authors show that a personalized approach, taking the phenotypic attributes of individual patients’ T cells into account, leads to more efficient CAR-T cell manufacturing and better CAR-T cell functionality.

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    • Kwasi Adu-Berchie
    • David J. Mooney
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  • Two new studies exploring PROTAC-mediated degradation of SMARCA2 for cancer therapy solve an apparently intractable selectivity challenge with SMARCA4 by utilising the requirement for a productive ternary complex between the protein, PROTAC and ligase complex.

    • John D. Harling
    • Christopher P. Tinworth
    Comment Open Access
  • Chalcogenide aerogels are receiving widespread attention due to their unique properties. Here we comment on a recent work about amorphous Na–Mn–Sn–S chalcogels featuring local structural control, and provide an outlook for the development of chalcogels and the metal-organic sulfide framework.

    • Lijun Yang
    • Jian Liu
    Comment Open Access
  • The development of photocatalysts is greatly hindered by false positives or non-reproducible data. Here, The authors describe the current known causes of non-reproducible results in the literature and present solutions to mitigate these false positive results.

    • Po-Wei Huang
    • Marta C. Hatzell
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  • In this work, Morgenstern and colleagues describe an approach involving functionalized nanobodies which decrease the activity of voltage-gated Ca2+ channels associated with β1 subunits and promote their removal from the surface membrane of neurons and muscle.

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