Honey bee workers take on different tasks as they age. The authors study the individuals' social networks and show that interaction patterns predict task allocation and developmental trajectories.
Subduction is the primary driver of plate tectonics, yet we still do not fully understand how subduction zones initiate or the budgets of life-supporting elements recycled via subduction. At Nature Communications, we advocate for more transdisciplinary initiatives and collaborative projects, which are essential if we are to continue to bring new dynamics to subduction research.
Our editors highlight articles they see as particularly interesting or important in these new pages spanning all research areas.
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Latest Research articles
Improving organic photovoltaic cells by forcing electrode work function well beyond onset of Ohmic transition
Both open-circuit voltage and fill factor of organic solar cells are affected by the metal-organic semiconductor interface. Here, the authors demonstrate that the voltage can continue to rise when the Fermi level is forced up to the semiconductor density-of-states tail.
Utilizing soft pumps in soft robotics is an attractive approach to endow untethered soft robots with muscle-like actuation. Here, the authors report bio-inspired soft electronic pumps as driving power sources to drive actuation and self-healing in untethered soft robotics.
Integrated sources of nonclassical light are a key component for scalable quantum technologies. Here, the authors work with two coupled microring resonators and show how to detune the resonances involved in unwanted parametric fluorescence, without significantly affecting the pump power efficiency.
Investigating biomembrane curvature formation is important for studying intracellular processes, but the instability of liposome models mimicking these membranes restricts exploration of membrane processes. Here, the authors demonstrate control over the curvature formation in polymersome membranes by insertion of PNIPAm as stimuli responsive polymer.
Self-powered ultraflexible photonic skin for continuous bio-signal detection via air-operation-stable polymer light-emitting diodes
Flexible electronic devices remain an attractive technology for optical sensor applications that require long-term health monitoring and conformability on human skin. Here, the authors report an ultrathin self-powered integrated organic optical system for plethysmogram monitoring.
- Astronomy and planetary science
- Energy science and technology
- Materials science
- Mathematics and computing
- Nanoscience and technology
- Optics and photonics
Climate models struggle to track the response of Arctic sea ice to warming, leading to efforts to improve sea-ice models. Here the author shows standard model metrics are poor judges of the impact of model improvements, but a new one, marginal ice zone fraction, is optimally suited to this task.
Tectonomagmatic conditions in the Precambrian were hypothesized to be unfavorable for porphyry Cu deposit formation. Here, the authors show that metallogenic processes typify Phanerozoic porphyry Cu deposits operated by ~1.88 Ga, reflecting modification of mantle lithosphere by oxidized slab-derived fluids at that time.
The conditions that shaped Earth’s evolution during the Archaean and Proterozoic Eons remain unknown. Using Lake Towuti in Indonesia as an analog of early oceans the authors find that microbial methanogenesis exerts a strong influence with important implications for the composition of Earth’s early atmosphere.
Superfund sites have hazardous wastes that could affect the health of those who live near them, but this has not been assessed across the USA. Here the authors find that proximity to superfund sites decreases life expectancy and is further exacerbated by sociodemographic and climate change factors.
Metabolic pathways inferred from a bacterial marker gene illuminate ecological changes across South Pacific frontal boundaries
Extracting functional information from 16S rRNA data surveys would provide a valuable tool for large-scale functional ecology. Here, the authors use PICRUSt2 to infer metabolic functions from bacterial marker gene data across the South Pacific Ocean, and compare them with rate data, biomass estimators and predictions based on shotgun metagenomes.
- Climate sciences
- Environmental sciences
- Environmental social sciences
- Natural hazards
- Ocean sciences
- Planetary science
- Solid Earth sciences
- Space physics
The tau protein has been implicated in neurodegenerative disorders and can propagate from cell to cell. Here, the authors show that tau acetylation reduces its degradation by chaperone-mediated autophagy, causing re-routing to other autophagic pathways and increasing extracellular tau release.
Redundant and non-redundant cytokine-activated enhancers control Csn1s2b expression in the lactating mouse mammary gland
Enhancers and promoters work together to actively regulate gene expression affecting several biological processes. Here, the authors provide molecular insights into the regulation of enhancers and super-enhancers in the Csn1s2b locus during lactation.
Toward integrative approaches to study the causal role of neural oscillations via transcranial electrical stimulation
Transcranial electrical stimulation techniques may enable exploration of the role of neural oscillations in the brain. Here, the authors provide a perspective on its potential across systems, species, theoretical and experimental scales.
Cancers in different populations have been shown to be genetically distinct. Here, the authors sequence breast cancers from Mexican-Hispanic patients and find that these patients have a higher percentage of Akt1 mutations compared to Caucasian and Asian populations, suggesting these are clinically actionable.
The molecular architecture of α-Synuclein (α-Syn) inclusions, pathognomonic of various neurodegenerative disorders, remains unclear. Here, authors use cryo-electron tomography to image neuronal α-Syn inclusions in situ and find that inclusions consist of α-Syn fibrils intermixed with cellular organelles without interacting directly.
- Biological techniques
- Cell biology
- Chemical biology
- Computational biology and bioinformatics
- Developmental biology
- Drug discovery
- Molecular biology
- Plant sciences
- Stem cells
- Structural biology
- Systems biology
Incidence and predictive biomarkers of Clostridioides difficile infection in hospitalized patients receiving broad-spectrum antibiotics
Here, the authors report the incidence of Clostridioides difficile infection (CDI) and assess potential clinical characteristics and biomarkers to predict CDI in 1,007 patients of 50 years and above receiving newly initiated antibiotic treatment.
TIM4 expression by dendritic cells mediates uptake of tumor-associated antigens and anti-tumor responses
Acquisition of dying tumor cell-associated antigens is an essential step for the initiation of anti-tumor immune response by conventional type 1 dendritic cells (cDC1). Here the authors show that the loss of TIM4 expression in lung tumor associated cDC1 is associated with less efficient uptake of cell associated antigens and reduction of CD8 + T cell activation in advanced lung tumors.
Clostridioides difficile infection (CDI) is the most common cause of antibiotic-associated diarrhoea (AAD); however, markers predictive of CDI or AAD development are as yet lacking. Here, to identify markers predictive of CDI, the authors profile the intestinal microbiota of 945 hospitalised patients from 34 hospitals in 6 different European countries and show distinct microbiota enriched in Enterococcus and depleted of Ruminococcus, Blautia, Prevotella and Bifidobacterium compared to non-CDI patients.
Peritoneal adhesions are a major cause of complications after abdominal surgery. Here the authors use a post-operative abdominal adhesion model in mice to show that resident F4/80HighCD206− macrophages form a protective barrier that can be enhanced by IL-4 administration or adoptive transfer of these cells.
Single cell transcriptional and chromatin accessibility profiling redefine cellular heterogeneity in the adult human kidney
Single cell transcriptomic and epigenomic sequencing of human kidney highlight diverse cell types and states. These findings help characterize a novel population of injured proximal tubule cells and illustrate the power of multi-omic approaches to characterizing human tissue.
- Health care
- Health occupations
- Medical research
- Molecular medicine
- Risk factors
- Signs and symptoms
Adverse climatic conditions are commonly reported to shape asylum migration, but their effect relative to other drivers is unknown. Here the authors compare climatic, economic, and political factors as predictors of future asylum flows to the EU and find that war and repression are the most important factors.
Efficiency stagnation in global steel production urges joint supply- and demand-side mitigation efforts
The effectiveness of large historical efforts for decarbonizing steel production is unclear. Here, the authors show that such efficiency gains were offset by a booming steel demand increase. This has led to a stagnating decarbonization progress over past decades, which jeopardizes realization of future climate targets.
The value assessment of job skills is critical for companies to select and retain the right talent and for individuals to develop them. Here the authors show that a data-driven method based on an enhanced neural network can assign meaningful value to job skills in a quantitative way and outperforms benchmark models for job salary prediction.
Recent technological, social, and educational changes are profoundly impacting our work, but what makes labour markets resilient to those labour shocks? Here, the authors show that labour markets resemble ecological systems whose resilience depends critically on the network of skill similarities between different jobs.
Precise knowledge of chemical composition and atomic structure of functional nanosized systems, such as metal clusters stabilized by an organic molecular layer, allows for detailed computational work to investigate structure-property relations. Here, we discuss selected recent examples of computational work that has advanced understanding of how these clusters work in catalysis, how they interact with biological systems, and how they can make self-assembled, macroscopic materials. A growing challenge is to develop effective new simulation methods that take into account the cluster-environment interactions. These new hybrid methods are likely to contain components from electronic structure theory combined with machine learning algorithms for accelerated evaluations of atom-atom interactions.
Equitable partnerships among the international volcano science community are important now more than ever, to cope with financial disparities and ultimately allow for worldwide volcano monitoring oriented to hazard mitigation.
A conversation on the effects of the COVID-19 pandemic on junior researchers’ careers with funders and university leaders
The various restrictions applied across the globe to contain the COVID-19 pandemic have been impacting the way we knew how to work. Dr. Matthews (a scientific program manager at the National Institute of Neurological Disorders and Stroke—NINDS), Dr. David del Álamo Rodriguez (head of the European Molecular Biology Organization—EMBO—fellowship program), and Dr. Gray (Associate Dean for the Sciences at the Advanced Science Research Center of the City University of New York) shared with Nature Communications their thoughts on how funders and university leadership can support early career researchers and young faculty through the COVID-19 pandemic.
The various restrictions applied across the globe to contain the COVID-19 pandemic have been impacting the way we knew how to work. Ms. Wilson (a PhD student in Earth System Science at Stanford University), Dr. Xin (a glia biologist and postdoctoral fellow at University of California San Francisco), and Dr. Saidaminov (a researcher in advanced functional materials and Assistant Professor at the University of Victoria) shared with Nature Communications their thoughts on how the COVID-19 pandemic is affecting their professional development and career progression and their coping strategies.
Replication inside macrophages is crucial for systemic dissemination of Salmonella in hosts. In a Nature Communications article, Jiang et al. show that Salmonella stimulates glycolysis and represses serine synthesis in macrophages, leading to accumulation of host glycolytic intermediates that the bacteria use as carbon source and as cues for its replication.
Liver cancer typically arises after years of inflammatory insults to hepatocytes. These cells can change their ploidy state during health and disease. Whilst polyploidy may offer some protection, new research shows it may also promote the formation of liver tumours.