Transonic buffet is a ubiquitous challenge in commercial aviation since it can result in catastrophic structural failure of the aircraft wings. Here, authors experimentally show that this critical aerodynamic phenomenon can be mitigated using a carefully designed porous trailing edge on the wing.

Ultra-low temperature resistant adhesives are desirable for their potential use in polar areas or space exploration. Here, the authors develop a low-temperature tolerant adhesive with high adhesion strength in a wide tolerable temperature range and long-lasting adhesion effect that exceeds the classic commercial hot melt adhesives.

Titanium has a strong affinity to oxygen, resulting in an increase in the manufacturing cost and complexity of the processes. Here the authors introduce a high-throughput technique using yttrium that can reduce the oxygen content in molten titanium to the level suitable for structural applications.

Multiple doping and low concentration of long-wavelength emitters suffer from repeatability and stability. Here, authors report singly-doped cluster-based white light-emitting system at high doping concentration of 30%, and optimize the charge and energy transfer based on antenna effect of ligands.

Quantum Hall ferromagnets can host magnons, collective spin-wave excitations, which have possible uses in spin-wave based information processing. Detecting these excitations electrically can be challenging. Here, Kumar, Srivastav, Roy, Park and coauthors demonstrate a noise-based approach to detecting magnons.

Synthetic apparel is a major contributor to global plastic leakage driven by mismanaged apparel waste.

Strong air-sea interactions during atmospheric rivers often lead to modest upper ocean heat changes. The authors show that interior ocean dynamics are compensating for these air-sea exchanges. These findings can help improve subseasonal forecasts.

The authors find a nonlinear, multiyear-long and country-heterogeneous economic loss induced by the Indian Ocean Dipole. Under a high emission scenario, the amplitude of the dipole is increasing, causing additional financial losses in the 21st century.

The b-value in earthquake size distribution shows spatiotemporal variations, being key to consider large-earthquake genesis. By high-precision focal mechanism data, we show a physical reason for the reduction in b-value before a major earthquake.

Findings of sulfide-volatile compound drops preserved in the Christiana-Santorini-Kolumbo volcanic field improve understanding of the fluxes of sulfur and metals during arc magmatism and associated ore deposit formation.

Theory predicts that adaptive mutations can have indirect negative effects on fitness. This study demonstrates how ‘adaptation begets adaptation’: changes to the sociogenetic environment accompanying rapid adaptation in wild crickets provoked genome-wide compensatory adaptation.

Individuals with autism often exhibit social memory impairment. Here, authors show the disruption of autism-associate Shank3 gene in more than a certain proportion of hippocampal ventral CA1 neurons impairs social memory, through AAV- and extracellular vesicle-mediated in vivo gene editing.

Unbiasedly benchmarking SRT computational methods remains a pressing challenge. Here, authors develop scCube, a simulation framework enabling scalable, reproducible, and unbiased generation of simulated SRT data, allowing researchers to benchmark and evaluate different methods.

Genetic testing is crucial for precision cancer medicine. Here, the authors develop a one-pot ERA-CRISPR assay to detect variable same-site indels, using an engineered AsCas12a variant with improved mismatch tolerance and broadened PAM scope.

Ferroptosis is of great importance in plant immunity including microbe-plant interactions. Here, the authors unveil that a regulated ferroptosis process is involved in the mutualistic symbiosis and disease resistance of endophyte OsiSh-2 and host rice.

Here, the authors provide evidence for the potential of CHIT1 concentration in the cerebrospinal fluid at diagnostic lumbar puncture as a biomarker for disability progression in multiple sclerosis (MS) as it reflects early microglial activation in active lesions of MS patients.

Poor access to suitable light-sheet microscopes remains a big obstacle for many end-users in biomedical research. Here, the authors present descSPIM, a low-cost, low-expertise light-sheet microscope for routine 3D imaging of cleared samples.

Genetic testing is crucial for precision cancer medicine. Here, the authors develop a one-pot ERA-CRISPR assay to detect variable same-site indels, using an engineered AsCas12a variant with improved mismatch tolerance and broadened PAM scope.

Here the authors present a framework for estimating disease risk using PGS accounting for country, age and sex. They find that PGSs have a significant sex-specific effect on common diseases, and their effect is typically larger in young individuals.

Site-directed insertion is a powerful approach for generating mutant lines but, historically, technically challenging. Here, the authors demonstrate CRIMP, an optimised protocol and universal toolkit (CRIMPkit), to greatly improve the efficacy of generating and studying mutant lines.

Synthetic apparel is a major contributor to global plastic leakage driven by mismanaged apparel waste.

The authors find a nonlinear, multiyear-long and country-heterogeneous economic loss induced by the Indian Ocean Dipole. Under a high emission scenario, the amplitude of the dipole is increasing, causing additional financial losses in the 21st century.

New and dynamically changing opportunities for commercial/private and civilian spaceflight raise the need for an examination of how to ethically guide space industry and community. This Perspective explores such considerations with respect to space traveler selection and human subject research.

Informal transportation services constitute the primary form of public transport in the Global South. Here, the authors analyze the structure of route networks in cities across the globe, showing how informal routes self-organize into consistent line services that often outperform centralized services in the Global North, exhibiting fewer detours and comparable interconnectivity.

The absence of an objective way of assessing freezing of gait in Parkinson’s Disease hinders research and care. A machine-learning contest using wearable sensor data delivered detection algorithms with high precision and identified time-of-day effects.