Focus
Focus on Autophagy
Autophagy targets damaged organelles and proteins for lysosomal degradation. This potent degradation mechanism has crucial roles in development, immune defence, programmed cell death, tumour suppression, neurodegeneration and stress response. The September 2010 issue of Nature Cell Biology presents a series of specially commissioned Reviews, Perspectives and Commentaries highlighting new insights into this process.
Editorial
Focus on Autophagy
Focusing on Autophagy-
Nature Cell Biology 12, p 813; (2010)
Full Text - Focusing on Autophagy | PDF - Focusing on Autophagy
Reviews
Focus on Autophagy
Eaten alive: a history of macroautophagy-
Zhifen Yang & Daniel J. Klionsky
Nature Cell Biology 12, pp 814–822; (2010)
Abstract - Eaten alive: a history of macroautophagy | Full Text - Eaten alive: a history of macroautophagy | PDF - Eaten alive: a history of macroautophagy
Focus on Autophagy
Autophagy in mammalian development and differentiation-
Noboru Mizushima & Beth Levine
Nature Cell Biology 12, pp 823–830; (2010)
Abstract - Autophagy in mammalian development and differentiation | Full Text - Autophagy in mammalian development and differentiation | PDF - Autophagy in mammalian development and differentiation
Perspectives
Focus on Autophagy
The origin of the autophagosomal membrane-
Sharon A. Tooze & Tamotsu Yoshimori
Nature Cell Biology 12, pp 831–835; (2010)
Abstract - The origin of the autophagosomal membrane | Full Text - The origin of the autophagosomal membrane | PDF - The origin of the autophagosomal membrane
Focus on Autophagy
Selective autophagy: ubiquitin-mediated recognition and beyond-
Claudine Kraft, Matthias Peter & Kay Hofmann
Nature Cell Biology 12, pp 836–841; (2010)
Abstract - Selective autophagy: ubiquitin-mediated recognition and beyond | Full Text - Selective autophagy: ubiquitin-mediated recognition and beyond | PDF - Selective autophagy: ubiquitin-mediated recognition and beyond
Commentary
Focus on Autophagy
Can autophagy promote longevity?-
Frank Madeo, Nektarios Tavernarakis & Guido Kroemer
Nature Cell Biology 12, pp 842–846; (2010)
Abstract - Can autophagy promote longevity? | Full Text - Can autophagy promote longevity? | PDF - Can autophagy promote longevity?