Systems-level analysis of the integrin adhesome to define the core cell adhesion machinery.p1577

Competition for actin between two distinct F-actin networks determines whether epithelial cells remain stationary or migrate.

[article p1435]

Both tissue-level and local stresses underlie germband extension in the Drosophila embryo.p1247

YAP and TAZ cooperate with AP-1 to regulate gene expression that controls cell proliferation and oncogenic growth.

[resource p1218]

Inhibition of NF-κB signalling or the downstream factor DOTL1 in aged fibroblasts increases their reprogramming efficiency.p1004

Microtubule initiation from a template is slow but the probability of initiation is increased by proteins that regulate microtubule dynamics.

[article p907]

Liver pre-metastatic niche, resulting from fibronectin overexpression by hepatic stellate cells in response to TGFβ produced by von Kupffer cells activated by pancreatic tumour-derived exosomes.p816

The F-actin binding protein WDR1 establishes planar polarity in the mouse embryonic epidermis by mediating tension.

[article p592]

Human fibroblasts plated on circular fibronectin islands show self-organization of the actin cytoskeleton into a chiral pattern.p445

Lysosomal calcium release stimulates calcineurin, which dephosphorylates and activates TFEB to control autophagy.

[article p288]

USP30 opposes parkin-mediated mitochondrial ubiquitylation.p160

AMBRA1 facilitates c-Myc degradation to control autophagy and cell proliferation.

[article p20]