The coordinated movement of endothelial cells involves the engulfment of cadherin-rich protrusions by follower cells.p1311

Esrrb is retained on mitotic chromosomes in ESCs and during early embryogenesis, and epigenetically marks key regulatory regions.

[article p1139]

Loss of LIFR–STAT3 signalling in metastatic breast cancer cells reduces expression of dormancy-related genes and promotes bone marrow colonization and osteoclastogenesis.p1078

Melanoma cells control the formation of a primary tumour niche by releasing microRNA-carrying melanosomes that are taken up by dermal fibroblasts leading to their activation.

[article p1006]

The lysosomal response to autophagic cargo during lysosome–autophagosome fusion involves TLR9 activation and OCRL recruitment.p839

Prolonged expression of p21 in p53-null cells triggers replication stress.

[article p777]

In vitro culture of human embryos reveals hallmarks of early human development and self-organizing capabilities.p700

Systematic analyses of mechanical signalling in cells on surfaces of different rigidities reveal a tunable rigidity threshold above which talin unfolds to mediate force transduction.

[article p540]

B cells are reprogrammed into iPSCs using C/EBPα and the Yamanaka factors OSKM, in a process that involves upregulation of Lsd1, Brd4 and Klf4.p371

Spatial scaffolding of cells by the extracellular matrix can control tube shapes and direct lumen elongation.

[letter p311]

Cultured human keratinocyte proliferation is either expanding, generating proliferating progeny, or balanced to produce both proliferating and differentiating progeny.p145

The centrosome promotes actin filament assembly through the activities of WASH and Arp2/3.

[article p65]