News & Views

  • News & Views |

    Wastewater testing captures the rise and fall of novel coronavirus cases in a mid-sized metropolitan region.

    • David A. Larsen
    •  & Krista R. Wigginton
  • News & Views |

    Interacting cells are characterized by sequencing FACS clusters.

    • Sean C. Bendall
  • News & Views |

    Machine learning provides a functional score for ~120,000 human phosphorylation sites.

    • Giulia Franciosa
    • , Ana Martinez-Val
    •  & Jesper V. Olsen
  • News & Views |

    In a step toward nanopore sequencing of proteins, an aerolysin pore discriminates many of the proteinogenic amino acids.

    • Stefan Howorka
    •  & Zuzanna S. Siwy
  • News & Views |

    Engineering perishable crops for use in indoor farms promises to expand the adoption of this high-yielding, efficient means of food production.

    • Cathryn A. O’Sullivan
    • , C. Lynne McIntyre
    • , Ian B. Dry
    • , Susan M. Hani
    • , Zvi Hochman
    •  & Graham D. Bonnett
  • News & Views |

    Information encoded in DNA can be stored in, and retrieved from, everyday objects.

    • Fahim Farzadfard
  • News & Views |

    A rapid method to introduce gene edits advances plant science.

    • Oliver Xiaoou Dong
    •  & Pamela C. Ronald
  • News & Views |

    Two studies offer a powerful strategy for combating bacterial blight in rice.

    • Rajeev K. Varshney
    • , Ian D. Godwin
    • , Trilochan Mohapatra
    • , Jonathan D. G. Jones
    •  & Susan R. McCouch
  • News & Views |

    Bacterial species that have eluded cultivation are selectively brought into culture.

    • William H. Lewis
    •  & Thijs J. G. Ettema
  • News & Views |

    Respiratory pathogens and the human immune response they elicit can now be studied in humanized mice.

    • Hergen Spits
    •  & Julien Villaudy
  • News & Views |

    Livers are stored in a supercooled state for extended periods, an approach that could expand access to liver transplantation.

    • Barry J. Fuller
    • , Alexander Petrenko
    •  & Edgardo Guibert
  • News & Views |

    Algorithms for building a variant-aware human graph genome enable fast and accurate genotyping without huge memory requirements.

    • Adam Ameur
  • News & Views |

    Nanopore sequencing of the sputum metagenome identifies respiratory pathogens in six hours.

    • Andrei Prodan
    • , Morten O. A. Sommer
    •  & Max Nieuwdorp
  • News & Views |

    The Kipoi repository provides a home for trained machine-learning models that facilitates their sharing and reuse.

    • Casey S. Greene
  • News & Views |

    A simple chemical modification can substantially reduce the toxicity of antisense oligonucleotides.

    • Arthur M. Krieg
  • News & Views |

    In vivo studies indicate that cytosine but not adenine base editors induce elevated levels of genome-wide off-target substitutions.

    • Jia Chen
    • , Bei Yang
    •  & Li Yang
  • News & Views |

    Human brain organoids are endowed with regional topography using engineered signaling centers.

    • Yuki Miura
    •  & Sergiu P. Pașca
  • News & Views |

    Large brain tissue sections are imaged with nanoscale resolution using expansion and lattice light sheet microscopy.

    • Weijian Yang
    •  & Rafael Yuste
  • News & Views |

    Cassava engineered to retain more iron and zinc faces challenges before moving into fields and onto forks.

    • Marc Ghislain
    • , Tawanda Muzhingi
    •  & Jan W. Low
  • News & Views |

    The generation of immature human oocytes in vitro highlights the challenges of folliculogenesis.

    • Jessica M Stringer
    •  & Patrick S Western
  • News & Views |

    siRNA delivery to the placenta silences the proteins responsible for preeclampsia.

    • Ana Sofia Cerdeira
    •  & Manu Vatish
  • News & Views |

    Two methods for measuring cross-reactivity could boost the safety of T-cell therapies.

    • Aswin Natarajan
    •  & Michelle Krogsgaard
  • News & Views |

    Screening patient-derived tumor cell cultures against a drug library is a promising adjunct to clinical decision-making.

    • Shumei Kato
    •  & Razelle Kurzrock
  • News & Views |

    The assembly of individual genomes from complex microbial communities is improved by sequencing of barcoded fragments.

    • Jacqueline Goordial
    •  & Jennifer Ronholm
  • News & Views |

    Massively parallel sequencing of peptides could signal a new era of high-throughput proteomics.

    • Ben C Collins
    •  & Ruedi Aebersold
  • News & Views |

    Invasive recordings of human brain activity predict mood fluctuations.

    • Amit Etkin
  • News & Views |

    A massive study informed by Design of Experiments uncovers factors that boost protein synthesis.

    • Thomas E Gorochowski
    •  & Tom Ellis
  • News & Views |

    A new model for representing genomes aims to capture the breadth of genetic diversity in populations.

    • Deanna M Church