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In spite of its modest performance in clinical trials, Benlysta may offer effective relief against lupus. But physicians are still working to identify the right patients. Michael Eisenstein reports.
By devoting funding to whole-genome studies, such as epigenetic and copy-number variation in stem cells, research on new genomic technology, and standards for methodologies and data collection/sharing, CIRM can spur both basic and translational research.
The NIH's proposed initiatives in translational science deserve solid financial backing from legislators and vocal support from the biomedical community.
As R&D costs spiral for drug developers, disruptive approaches to clinical trial design and management are gaining traction. Get ready for electronic data capture, precompetitive data sharing, virtual trials and a variety of bold new paradigms.