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Targeting double-stranded nucleic acids using the λExo–pDNA system
λ exonuclease (λExo) binds 5′-phosphorylated single-stranded DNA (pDNA) at complementary regions on double-stranded DNA and DNA–RNA duplexes under ambient conditions without a PAM-like motif. In the presence of Mg2+, λExo then digests the pDNA into nucleotides.
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Navigating the vaccines landscape
We explore the latest developments in the vaccines field, through our editorial feature and showcase of companies.
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Rapid customization of Solanaceae fruit crops for urban agriculture
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Insect resistance management in GM crops: past, present and future
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Efficient genetic code expansion without host genome modifications
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Organoid culture promotes dedifferentiation of mouse myoblasts into stem cells capable of complete muscle regeneration