Volume 473 Issue 7347, 19 May 2011

The Canadian Arctic Archipelago contains one-third of the global volume of land ice outside the ice sheets, but its contribution to sea-level change is largely unknown. Gardner et al. use three independent techniques to reveal that mass loss from the archipelago was 92 ±12 gigatonnes per year in 2007–09, about three times greater than in 2004–06, and coincident with warmer summer temperatures. The record is too short to allow a firm conclusion on longer-term trends, but it is clear that the Canadian Arctic Archipelago is a significant contributor to sea-level rise. On the cover, an englacial melt channel within the Devon Island ice cap. Photo credit: Angus Duncan.

Editorial

  • Editorial |

    An accusation that referees are too demanding and editors too supine demands a response. Authors, editors and referees all have lessons to learn.

  • Editorial |

    Targeted therapies work, but need help to fulfil their potential.

  • Editorial |

    Official recognition for the Anthropocene would focus minds on the challenges to come.

World View

Research Highlights

Seven Days

News

News Feature

  • News Feature |

    The United States has abandoned comprehensive greenhouse-gas curbs, but California is pressing ahead. Mary Nichols is leading the fight against emissions.

    • Jeff Tollefson

Comment

  • Comment |

    Nokia, Toyota and Roche explain how they are weathering the financial crash, the technologies they are investing in and their innovation strategies.

Correction

Books & Arts

  • Books & Arts |

    A clever play shows how engineer Sergei Korolyov drove the Soviet space programme, finds Philip Ball.

    • Philip Ball
  • Books & Arts |

    Charles Jencks designs landscapes and sculptures to convey concepts in astronomy, biology and mathematics — notably at CERN, Europe's particle-physics lab near Geneva, Switzerland, and in his Garden of Cosmic Speculation near Dumfries in Scotland, UK. On the launch of his new book, he discusses green architecture and metaphor.

    • Jascha Hoffman

Correspondence

Obituary

News & Views

  • News & Views |

    Conservationists predict massive extinctions as a result of habitat loss. Habitat loss undoubtedly does drive extinctions, but dealing with an unmet assumption that underlies these predictions yields much lower estimates. See Letter p.368

    • Carsten Rahbek
    •  & Robert K. Colwell
  • News & Views |

    Two teams searching for extrasolar planets have jointly discovered a new population of objects: ten Jupiter-mass planets far from their host stars, or perhaps even floating freely through the Milky Way. See Letter p.349

    • Joachim Wambsganss
  • News & Views |

    In October 1998, a hurricane visited death and destruction on Honduras, with flooding and mudslides. A case history of a rural community documents how recovery from that event produced socio-economic improvement.

    • Arun Agrawal
  • News & Views |

    Melting and solidification of iron alloys in Earth's core may explain structural complexity in the solid inner core, and alter the way we think about the dynamics of the deep interior. See Letter p.361

    • Bruce Buffett
  • News & Views |

    Tet proteins mediate the hydroxymethylation of DNA. New work reveals their function in gene regulation and the extent of their activity throughout the genome of embryonic stem cells. See Article p.343 & Letters p.389 , p.394 & p.398

    • Nathalie Véron
    •  & Antoine H. F. M. Peters
  • News & Views |

    The Casparian strip in plant roots is a diffusion barrier that directs water and solutes from the soil to the water-conducting tissues. Proteins involved in making the strip have at long last been identified. See Letter p.380

    • Markus Grebe

Editorial

Review Article

Article

Letter

  • Letter |

    • T. Sumi
    • , K. Kamiya
    • , D. P. Bennett
    • , I. A. Bond
    • , F. Abe
    • , C. S. Botzler
    • , A. Fukui
    • , K. Furusawa
    • , J. B. Hearnshaw
    • , Y. Itow
    • , P. M. Kilmartin
    • , A. Korpela
    • , W. Lin
    • , C. H. Ling
    • , K. Masuda
    • , Y. Matsubara
    • , N. Miyake
    • , M. Motomura
    • , Y. Muraki
    • , M. Nagaya
    • , S. Nakamura
    • , K. Ohnishi
    • , T. Okumura
    • , Y. C. Perrott
    • , N. Rattenbury
    • , To. Saito
    • , T. Sako
    • , D. J. Sullivan
    • , W. L. Sweatman
    • , P. J. Tristram
    • , P. C. M. Yock
    • , A. Udalski
    • , M. K. Szymański
    • , M. Kubiak
    • , G. Pietrzyński
    • , R. Poleski
    • , I. Soszyński
    • , Ł. Wyrzykowski
    •  & K. Ulaczyk
  • Letter |

    • H. Agakishiev
    • , M. M. Aggarwal
    • , Z. Ahammed
    • , A. V. Alakhverdyants
    • , I. Alekseev
    • , J. Alford
    • , B. D. Anderson
    • , C. D. Anson
    • , D. Arkhipkin
    • , G. S. Averichev
    • , J. Balewski
    • , D. R. Beavis
    • , N. K. Behera
    • , R. Bellwied
    • , M. J. Betancourt
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    • , A. Bhasin
    • , A. K. Bhati
    • , H. Bichsel
    • , J. Bielcik
    • , J. Bielcikova
    • , B. Biritz
    • , L. C. Bland
    • , I. G. Bordyuzhin
    • , W. Borowski
    • , J. Bouchet
    • , E. Braidot
    • , A. V. Brandin
    • , A. Bridgeman
    • , S. G. Brovko
    • , E. Bruna
    • , S. Bueltmann
    • , I. Bunzarov
    • , T. P. Burton
    • , X. Z. Cai
    • , H. Caines
    • , M. Calderon
    • , D. Cebra
    • , R. Cendejas
    • , M. C. Cervantes
    • , Z. Chajecki
    • , P. Chaloupka
    • , S. Chattopadhyay
    • , H. F. Chen
    • , J. H. Chen
    • , J. Y. Chen
    • , L. Chen
    • , J. Cheng
    • , M. Cherney
    • , A. Chikanian
    • , K. E. Choi
    • , W. Christie
    • , P. Chung
    • , M. J. M. Codrington
    • , R. Corliss
    • , J. G. Cramer
    • , H. J. Crawford
    • , A. Davila Leyva
    • , L. C. De Silva
    • , R. R. Debbe
    • , T. G. Dedovich
    • , A. A. Derevschikov
    • , R. Derradi de Souza
    • , L. Didenko
    • , P. Djawotho
    • , S. M. Dogra
    • , X. Dong
    • , J. L. Drachenberg
    • , J. E. Draper
    • , J. C. Dunlop
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    • , L. Eun
    • , O. Evdokimov
    • , R. Fatemi
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    • , R. G. Fersch
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    • , S. Heppelmann
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    • , B. Huang
    • , H. Z. Huang
    • , T. J. Humanic
    • , L. Huo
    • , G. Igo
    • , P. Jacobs
    • , W. W. Jacobs
    • , C. Jena
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    • , J. Joseph
    • , E. G. Judd
    • , S. Kabana
    • , K. Kang
    • , J. Kapitan
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    • , D. Keane
    • , A. Kechechyan
    • , D. Kettler
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    • , A. Kisiel
    • , V. Kizka
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    • , L. Koroleva
    • , W. Korsch
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    • , P. Kravtsov
    • , K. Krueger
    • , M. Krus
    • , L. Kumar
    • , P. Kurnadi
    • , M. A. C. Lamont
    • , J. M. Landgraf
    • , S. LaPointe
    • , J. Lauret
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    • , R. Lednicky
    • , J. H. Lee
    • , W. Leight
    • , M. J. LeVine
    • , C. Li
    • , L. Li
    • , N. Li
    • , W. Li
    • , X. Li
    • , X. Li
    • , Y. Li
    • , Z. M. Li
    • , M. A. Lisa
    • , F. Liu
    • , H. Liu
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    • , T. Ljubicic
    • , W. J. Llope
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    • , X. Luo
    • , G. L. Ma
    • , Y. G. Ma
    • , D. P. Mahapatra
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    • , O. I. Mall
    • , R. Manweiler
    • , S. Margetis
    • , C. Markert
    • , H. Masui
    • , H. S. Matis
    • , Yu. A. Matulenko
    • , D. McDonald
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    • , A. Meschanin
    • , R. Milner
    • , N. G. Minaev
    • , S. Mioduszewski
    • , M. K. Mitrovski
    • , Y. Mohammed
    • , B. Mohanty
    • , M. M. Mondal
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    • , M. G. Munhoz
    • , M. K. Mustafa
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    • , P. K. Netrakanti
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    • , B. S. Page
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    • , H. Pei
    • , T. Peitzmann
    • , C. Perkins
    • , W. Peryt
    • , P. Pile
    • , M. Planinic
    • , M. A. Ploskon
    • , J. Pluta
    • , D. Plyku
    • , N. Poljak
    • , J. Porter
    • , A. M. Poskanzer
    • , B. V. K. S. Potukuchi
    • , C. B. Powell
    • , D. Prindle
    • , C. Pruneau
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    • , P. R. Pujahari
    • , J. Putschke
    • , H. Qiu
    • , R. Raniwala
    • , S. Raniwala
    • , R. L. Ray
    • , R. Redwine
    • , R. Reed
    • , H. G. Ritter
    • , J. B. Roberts
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    • , J. L. Romero
    • , L. Ruan
    • , J. Rusnak
    • , N. R. Sahoo
    • , I. Sakrejda
    • , S. Salur
    • , J. Sandweiss
    • , E. Sangaline
    • , A. Sarkar
    • , J. Schambach
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    • , A. M. Schmah
    • , N. Schmitz
    • , T. R. Schuster
    • , J. Seele
    • , J. Seger
    • , I. Selyuzhenkov
    • , P. Seyboth
    • , N. Shah
    • , E. Shahaliev
    • , M. Shao
    • , M. Sharma
    • , S. S. Shi
    • , Q. Y. Shou
    • , E. P. Sichtermann
    • , F. Simon
    • , R. N. Singaraju
    • , M. J. Skoby
    • , N. Smirnov
    • , D. Solanki
    • , P. Sorensen
    • , H. M. Spinka
    • , B. Srivastava
    • , T. D. S. Stanislaus
    • , D. Staszak
    • , S. G. Steadman
    • , J. R. Stevens
    • , R. Stock
    • , M. Strikhanov
    • , B. Stringfellow
    • , A. A. P. Suaide
    • , M. C. Suarez
    • , N. L. Subba
    • , M. Sumbera
    • , X. M. Sun
    • , Y. Sun
    • , Z. Sun
    • , B. Surrow
    • , D. N. Svirida
    • , T. J. M. Symons
    • , A. Szanto de Toledo
    • , J. Takahashi
    • , A. H. Tang
    • , Z. Tang
    • , L. H. Tarini
    • , T. Tarnowsky
    • , D. Thein
    • , J. H. Thomas
    • , J. Tian
    • , A. R. Timmins
    • , D. Tlusty
    • , M. Tokarev
    • , T. A. Trainor
    • , S. Trentalange
    • , R. E. Tribble
    • , P. Tribedy
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    • , G. van Nieuwenhuizen
    • , J. A. Vanfossen Jr
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    • , F. Videbaek
    • , Y. P. Viyogi
    • , S. Vokal
    • , S. A. Voloshin
    • , M. Wada
    • , M. Walker
    • , F. Wang
    • , G. Wang
    • , H. Wang
    • , J. S. Wang
    • , Q. Wang
    • , X. L. Wang
    • , Y. Wang
    • , G. Webb
    • , J. C. Webb
    • , G. D. Westfall
    • , C. Whitten Jr.
    • , H. Wieman
    • , S. W. Wissink
    • , R. Witt
    • , W. Witzke
    • , Y. F. Wu
    • , Z. Xiao
    • , W. Xie
    • , H. Xu
    • , N. Xu
    • , Q. H. Xu
    • , W. Xu
    • , Y. Xu
    • , Z. Xu
    • , L. Xue
    • , Y. Yang
    • , Y. Yang
    • , P. Yepes
    • , K. Yip
    • , I-K. Yoo
    • , M. Zawisza
    • , H. Zbroszczyk
    • , W. Zhan
    • , J. B. Zhang
    • , S. Zhang
    • , W. M. Zhang
    • , X. P. Zhang
    • , Y. Zhang
    • , Z. P. Zhang
    • , F. Zhao
    • , J. Zhao
    • , C. Zhong
    • , W. Zhou
    • , X. Zhu
    • , Y. H. Zhu
    • , R. Zoulkarneev
    •  & Y. Zoulkarneeva.
  • Letter |

    • Benjamin K. Attwood
    • , Julie-Myrtille Bourgognon
    • , Satyam Patel
    • , Mariusz Mucha
    • , Emanuele Schiavon
    • , Anna E. Skrzypiec
    • , Kenneth W. Young
    • , Sadao Shiosaka
    • , Michal Korostynski
    • , Marcin Piechota
    • , Ryszard Przewlocki
    •  & Robert Pawlak
  • Letter |

    • Cihangir Duy
    • , Christian Hurtz
    • , Seyedmehdi Shojaee
    • , Leandro Cerchietti
    • , Huimin Geng
    • , Srividya Swaminathan
    • , Lars Klemm
    • , Soo-mi Kweon
    • , Rahul Nahar
    • , Melanie Braig
    • , Eugene Park
    • , Yong-mi Kim
    • , Wolf-Karsten Hofmann
    • , Sebastian Herzog
    • , Hassan Jumaa
    • , H. Phillip Koeffler
    • , J. Jessica Yu
    • , Nora Heisterkamp
    • , Thomas G. Graeber
    • , Hong Wu
    • , B. Hilda Ye
    • , Ari Melnick
    •  & Markus Müschen
  • Letter |

    • William A. Pastor
    • , Utz J. Pape
    • , Yun Huang
    • , Hope R. Henderson
    • , Ryan Lister
    • , Myunggon Ko
    • , Erin M. McLoughlin
    • , Yevgeny Brudno
    • , Sahasransu Mahapatra
    • , Philipp Kapranov
    • , Mamta Tahiliani
    • , George Q. Daley
    • , X. Shirley Liu
    • , Joseph R. Ecker
    • , Patrice M. Milos
    • , Suneet Agarwal
    •  & Anjana Rao

Technology Feature

  • Technology Feature |

    Biologists have copied an existing genetic code, but haven't yet commercialized it or written their own. What will it take for a tour de force to reach industrial force?

    • Monya Baker

Feature

Q&A

  • Q&A |

    An analytical chemist turned neuroscientist probes fruitfly brain function.

    • Virginia Gewin

Futures

  • Futures |

    The word on the street.

    • Julian Tang

Insight

  • Insight |

    Cardiovascular Biology

    A healthy vasculature is vital for our survival. Vascular dysfunction is linked to diverse diseases and can lead to heart failure and death. Uncovering how blood vessels grow and function during normal and disease conditions has enormous potential for improving human health, and this exciting research area is developing at a rapid pace.

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