Reviews & Analysis

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  • Wnt signalling molecules are thought to direct the development of an organism by spreading through tissues. But flies grow with almost normal appendages even when their main Wnt protein cannot move. Two scientists discuss the implications of this finding for our understanding of development. See Article p.180

    • Ginés Morata
    • Gary Struhl
    News & Views
  • A marriage between satellite observations and modelling has shown that acceleration of electrons in the magnetosphere can be explained by scattering of these particles by plasma oscillations known as chorus waves. See Letter p.411

    • Mary K. Hudson
    News & Views
  • Studies in mice and humans suggest that cellular senescence, the cessation of cell proliferation that is known to suppress cancer and promote ageing, may have evolved to regulate embryonic development.

    • Judith Campisi
    News & Views
  • Superconducting quantum circuits are the core technology behind the most sensitive magnetometers. An analogous device has now been implemented using a gas of ultracold atoms, with possible applications for rotation sensing.

    • Charles A. Sackett
    News & Views
  • Adapted extracts from selected News & Views articles published this year.

    News & Views
  • The thermal history of thousands of rock samples convincingly confirms the idea that climate cooling accelerates the rate of erosion at Earth's surface — and implicates glaciers in particular. See Letter p.423

    • David Lundbek Egholm
    News & Views
  • A series of in vitro, genomic, ecological and epidemiological studies has pinpointed gene mutations in the malaria parasite Plasmodium falciparum that play a key part in resistance to artemisinin-based antimalarial drugs. See Article p.50

    • Christopher V. Plowe
    News & Views
  • Adding the first high-quality Neanderthal sequence to genomic comparisons of archaic and modern humans sheds light on gene flow, population structure and adaptation, and suggests the existence of an unknown group. See Article p.43

    • Ewan Birney
    • Jonathan K. Pritchard
    News & Views
  • Recent experience can affect memory either positively or negatively. A small population of inhibitory neurons that express the protein parvalbumin seems to have a pivotal role in this process. See Letter p.272

    • Kevin Allen
    • Hannah Monyer
    News & Views
  • A three-dimensional climate model indicates that the fraction of Sun-like stars that might harbour a rocky planet within their habitable zone could be smaller than previously estimated. See Letter p.268

    • James F. Kasting
    • Chester E. Harman
    News & Views
  • The idea of creating liquids containing magnetic particles that display ferromagnetism has not been realized — until now. Plate-shaped magnets in a liquid crystal have been made that exhibit this property. See Article p.237

    • Noel A. Clark
    News & Views
  • Mechanical stresses that are intrinsic to the early shape-forming movements of embryonic tissues have now been shown to play essential and evolutionarily conserved parts in cell-fate specification.

    • Stefano Piccolo
    News & Views
  • The discovery of a protein that is targeted for degradation by the 'witch' hormones called strigolactones reveals a mechanism by which shoot architecture is controlled in rice plants. See Articles p.401 & p.406

    • Steven M. Smith
    News & Views
  • The collective motions of dwarf galaxies in planes around the Andromeda galaxy and the Milky Way have presented a challenge to theory. Interactions between galaxy groups in the distant past may have left their imprint on these dwarfs.

    • Alan McConnachie
    News & Views
  • Accumulating evidence that the eukaryotic nuclear lineage originated from within the Archaea provides support for a tree containing only two primary domains of life—the Achaea and Bacteria—over the currently accepted ‘three-domains tree’.

    • Tom A. Williams
    • Peter G. Foster
    • T. Martin Embley
    Review Article
  • Observations of a high degree of polarization in the immediate optical afterglow of a γ-ray burst indicate that these powerful cosmic explosions carry large-scale, ordered magnetic fields. See Letter p.119

    • Maxim Lyutikov
    News & Views
  • An ultrafast mode of vesicle endocytosis — a crucial process occurring at neural junctions that underpins brain function — has been uncovered. Long-standing models of endocytosis will therefore need to be re-evaluated. See Article p.242

    • Soyoun Cho
    • Henrique von Gersdorff
    News & Views
  • Structures of the heat-sensitive TRPV1 ion channel have been solved using single-particle electron cryo-microscopy, representing a landmark in the use of this technique for structural biology. See Articles p.107 & p.113

    • Richard Henderson
    News & Views
  • The status of the protein p53 determines whether inhibiting the cellular autophagy pathway promotes or inhibits pancreatic cancer in mice. This finding serves as a cautionary tale for clinical trials of autophagy inhibitors. See Letter p.296

    • Hanna Starobinets
    • Jayanta Debnath
    News & Views
  • As the recipients of the 2013 science Nobel prizes gather in Stockholm to celebrate and be celebrated, News & Views shares some expert opinions on the achievements honoured.

    • Walter Thiel
    • Gerhard Hummer
    News & Views