Reviews & Analysis

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  • The rise of malaria in Africa is a subject of much debate. A new analysis emphasizes the influence of rainfall, but there appear to be few areas where climate has been a major driver of this change.

    • Christopher Thomas
    News & Views
  • Damaged DNA must be removed with the utmost precision, as mistakes are costly. The structure of a repair enzyme bound to its substrate provides a welcome clue to how this is achieved.

    • Tomas Lindahl
    News & Views
  • A long-awaited breakthrough has been made in lattice quantum chromodynamics — a means of calculating the effect of the strong force between sub-atomic particles that could, ultimately, unveil new physics.

    • Ian Shipsey
    News & Views
  • The silicon chip has been the mainstay of the electronics industry and it may similarly come to dominate photonics. A key component — a high-frequency optical modulator — has now been fabricated.

    • Graham T. Reed
    News & Views
  • In an echo of events that unfolded earlier in the West, declines of vulture populations in the Indian subcontinent are linked to an environmental poison. Three species of these birds approach extinction.

    • Robert Risebrough
    News & Views
  • The causes of defects in the blood system of newborn babies can be hard to establish if the errors are not inherited. An elegant approach has identified a gene that can encourage new blood vessels to grow.

    • Diether Lambrechts
    • Peter Carmeliet
    News & Views
  • Some species of plant will prefer a world with higher levels of atmospheric carbon dioxide. When those species are invasive pests, the invaders may well flourish at the expense of the native vegetation.

    • Peter D. Moore
    News & Views
  • A neglected mathematical theory is enjoying new popularity, thanks to its relevance to network dynamics in biological systems. The beating of a leech's heart is just one example that has a mathematical basis in ‘groupoid theory’.

    • Ian Stewart
    News and Views Feature
  • Ammonia is produced industrially by combining nitrogen and hydrogen gas, catalysed over a solid iron surface. How about a catalytic reaction that could take place in solution? The first steps have now been taken.

    • Michael D. Fryzuk
    News & Views
  • Nerve transmission depends on voltage-gated ion-channel proteins, which in turn depend on the behaviour of a membrane domain called the voltage sensor. Therein lies the latest episode in a continuing story.

    • Robert O. Blaustein
    • Christopher Miller
    News & Views
  • Comparative genetic linkage studies in rats, mice and humans have finally identified a key component of vitamin K metabolism that is targeted by the commonest anticoagulant drugs in use today.

    • J. Evan Sadler
    News & Views
  • A surprising number of the icy objects in the Kuiper belt exist in pairs, or binaries. A new model proposes that these two-body systems were created through three-body interactions.

    • Joseph A. Burns
    News & Views
  • During egg and sperm production, the two copies of a duplicated chromosome must be bound together until it is time for their separation. A protein that protects this chromosomal glue has now been discovered.

    • Robin Allshire
    News & Views