Reviews & Analysis

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  • The material graphene has a vast number of potential applications — but a survey of commercially available graphene samples reveals that research could be undermined by the poor quality of the available material.

    • Peter Bøggild
    News & Views
  • The bacterial-defence system CRISPR–Cas can store DNA snippets that correspond to encountered viral RNA sequences. One such system has now been harnessed to record gene expression over time in bacteria.

    • Chase L. Beisel
    News & Views
  • An organic polymer exhibits a phase transition that is associated with improved electromechanical properties. This feature links organic polymers with widely used perovskite materials, and could have many applications.

    • Ronald E. Cohen
    News & Views
  • Antiviral drugs prevent HIV from replicating, but the virus can hide in the cells of infected individuals in a non-replicating, latent form. A two-pronged approach to target this latent virus shows promise in monkeys.

    • Sharon R. Lewin
    News & Views
  • In developing embryos, molecular and physical differences divide the cells that will form eggs or sperm and those that will form the body. The mouse protein OTX2 directs this decision by blocking reproductive-cell fate.

    • Diana J. Laird
    News & Views
  • Asgard archaea are the closest known relatives of nucleus-bearing organisms called eukaryotes. A study indicates that these archaea have a dynamic network of actin protein — a trait thought of as eukaryote-specific.

    • Laura Eme
    • Thijs J. G. Ettema
    News & Views
  • The current state of the search for dark-matter particles is reviewed, and a broader experimental and theoretical approach is proposed to solve the dark-matter problem.

    • Gianfranco Bertone
    • Tim M. P. Tait
    Review Article
  • What Nature was saying 50 and 100 years ago.

    News & Views
  • The movements of relocated wild animals reveal that a lost migratory skill was regained over successive generations. This suggests that skill improvements can occur over time as animals learn expertise from each other.

    • Andrew Whiten
    News & Views
  • Current biological sensors require bulky external power sources. Ultrathin solar cells have now been fabricated that can power flexible, wearable sensors for the precise and continuous monitoring of biological signals.

    • Shiming Zhang
    • Fabio Cicoira
    News & Views
  • Contrary to previous assumptions, it seems the cells that line blood vessels are derived from more than one source. In addition to their known developmental path, they can arise from progenitors of embryonic blood cells.

    • M. Luisa Iruela-Arispe
    News & Views
  • Increases in biomechanical forces in the liver’s blood vessels have now been shown to activate two mechanosensitive proteins. The proteins trigger blood-vessel cells to deploy regenerative factors that drive liver growth.

    • Sina Y. Rabbany
    • Shahin Rafii
    News & Views
  • Mechanical structures have been made that exhibit self-guided, multi-step sequences of shape changes in response to an applied force. Such structures could have applications in flexible electronics and soft robotics.

    • Larry L. Howell
    News & Views
  • Drug treatments for HIV infection require the long-term use of daily medication that can have toxic side effects. A pair of HIV-targeting antibodies might offer an alternative therapeutic approach.

    • Nancy L. Haigwood
    News & Views
  • What Nature was saying 50 and 100 years ago.

    News & Views
  • Aggregation of the protein tau is implicated in neurodegenerative diseases in humans. It emerges that eliminating a type of damaged cell that no longer divides can prevent tau-mediated neurodegeneration in mice.

    • Jay Penney
    • Li-Huei Tsai
    News & Views
  • Chromosomes can exist outside the nucleus in rupture-prone structures called micronuclei. It emerges that micronuclei are fragile because their outer layer lacks some nuclear-envelope components.

    • Matthias Samwer
    • Daniel W. Gerlich
    News & Views
  • Photoemission, the ejection of an electron from a material on the absorption of a photon, is one of the fastest processes in nature. An experiment demonstrates how the dynamics of this process can be captured in real time.

    • Thomas Fennel
    News & Views
  • The sleep disorder narcolepsy is linked to immune-system genes and is caused by the loss of neurons that express the protein hypocretin. Hypocretin-targeting immune cells have now been found in people with narcolepsy.

    • Roland S. Liblau
    News & Views
  • Experiments show that short bunches of protons can produce electric fields that are strong enough to accelerate energetic electrons compactly. This discovery could lead to miniaturized high-energy particle accelerators.

    • Toshiki Tajima
    News & Views