Structural Biology

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  • A new solution structure of the oligomerization domain of p53 provides a framework for interpreting a wealth of biochemical data but casts doubt on details of an earlier structure.

    • Christopher Surridge
    Structural Biology
  • Structural insight into the trimeric organization of the human mannose-binding protein sheds light on the workings of the non-clonal, innate immune response in vertebrates.

    • Guy Riddihough
    Structural Biology
  • A double insight into visual accommodation by the eye lens in birds and into the activity of a superfamily of metabolic enzymes is provided by the structure of turkey lens Scrystallin.

    • Guy Riddihough
    Structural Biology
  • Redox-dependent changes in the position of bound water inside cytochrome c in solution may be important for its function as an electron transfer protein.

    • Christopher Surridge
    Structural Biology