Articles in 2014

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  • Governments that want the natural sciences to deliver more for society need to show greater commitment towards the social sciences and humanities.

  • Nature looks at what the New Year holds for science.

    • Elizabeth Gibney
  • From Gradzilla to coffee consumption: the research enterprise quantified for the year to come.

    • Mark Zastrow
    News Feature
  • A guide to the popular, free statistics and visualization software that gives scientists control of their own data analysis.

    • Sylvia Tippmann
  • Water is becoming more scarce as populations increase, potentially leading to conflict. The age of hydro-diplomacy is upon us, says Jan Eliasson.

    • Jan Eliasson
    World View
  • Collective behaviour in animal groups can improve individual perception and decision-making, but the neural mechanisms involved have been hard to access in classic models for these phenomena; here it is shown that Drosophila’s olfactory responses are enhanced in groups of flies, through mechanosensory neuron-dependent touch interactions.

    • Pavan Ramdya
    • Pawel Lichocki
    • Richard Benton
  • The long elusive mammalian meiosis-specific kinetochore factor has been identified in mice; MEIKIN—which plays an equivalent role to the yeast proteins Spo13 and Moa1—ensures mono-orientation, protects sister chromatid cohesion and recruits the kinase PLK1 to the kinetochores.

    • Jihye Kim
    • Kei-ichiro Ishiguro
    • Yoshinori Watanabe
  • Up to half of children with severe developmental disorders of probable genetic origin remain without a genetic diagnosis; here, in a systematic and nationwide study of 1,133 children with severe, undiagnosed developmental disorders, and their parents, exome sequencing and array-based detection of chromosomal rearrangements reveals novel genes causing developmental disorders, increasing the proportion of children that can now be diagnosed to 31%.

    • T. W. Fitzgerald
    • S. S. Gerety
    • M. E. Hurles
  • The full complement of transcriptional regulators that affect synthesis of the plant secondary cell wall remains largely undetermined; here, the network of protein–DNA interactions controlling secondary cell wall synthesis of Arabidopsis thaliana is determined, showing that gene expression is regulated by a series of feed-forward loops to ensure that the secondary cell wall is deposited at the right time and in the right place.

    • M. Taylor-Teeples
    • L. Lin
    • S. M. Brady
  • Lineage-tracing experiments identify a rare, undifferentiated population of quiescent cells in the mouse distal lung that are activated through a Notch signalling pathway to repair the epithelium after bleomycin- or influenza-mediated injury; inappropriate Notch signalling may be a major contributor to failed regeneration within the lungs of patients with chronic lung disease.

    • Andrew E. Vaughan
    • Alexis N. Brumwell
    • Harold A. Chapman
  • Top medical journals filter out poor papers but often reject future citation champions.

    • Mark Peplow