Outlook

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  • Stem-cell therapy promises to restore motor function after a stroke or spinal-cord injury, but neurologists are proceeding with caution.

    • Katherine Bourzac
    Outlook
  • Adult stem cells have become a regulatory battleground as clinicians, scientists and ethicists debate whether the road to the clinic should be shorter.

    • Michael Eisenstein
    Outlook
  • Multiple sclerosis often strikes between the ages of 20 and 40, when people are entering the workforce and raising families.

    • Charles Schmidt
    Outlook
  • Dietary changes may be able to alleviate the symptoms of multiple sclerosis, but testing the effects of diet will need a different protocol to the one used for drugs.

    • Sujata Gupta
    Outlook
  • It is time for a bolder approach to developing drugs for progressive multiple sclerosis, says Bibi Bielekova.

    • Bibi Bielekova
    Outlook
  • New drugs are beginning to show promise for people with one of the less common, and harder to treat, forms of multiple sclerosis.

    • Elie Dolgin
    Outlook
  • Emerging evidence points to a viral infection, low levels of vitamin D and genetics as culprits in multiple sclerosis, but how they combine to cause the disease is unclear.

    • Carolyn Brown
    Outlook
  • The characteristic brain pathology and motor symptoms of Parkinson's disease are well established. But the details of the disease's cause and course are much murkier.

    • Sarah Deweerdt
    Outlook
  • Deep brain stimulation is a proven treatment for Parkinson's disease. The only thing left to find out is how it works.

    • Michael Eisenstein
    Outlook
  • By bootstrapping existing technologies, researchers can gain a minute-by-minute understanding of a patient's disease.

    • Lauren Gravitz
    Outlook
  • In the 200 years since Parkinson's disease was first described, the understanding and management of the disease has come a long way. But researchers have yet to unlock all of its secrets. By Liam Drew.

    • Liam Drew
    Outlook
  • Biomarkers will be essential if research on Parkinson's is to progress, but their discovery depends on scientists sharing data, says Mark Frasier.

    • Mark Frasier
    Outlook
  • Non-motor symptoms such as sleep disorders and a poor sense of smell may hold the key to diagnosing Parkinson's disease before the characteristic tremor starts.

    • Katherine Bourzac
    Outlook
  • A controversial theory that could revolutionize our understanding of Parkinson's disease is gaining ground. But not everybody is convinced that misfolded proteins that spread in the brain are the cause of the disease.

    • Simon Makin
    Outlook
  • Scientists have theories about dark matter and dark energy — and some observations — but both are poorly understood. Here are four of their biggest questions.

    • Neil Savage
    Outlook
  • Astronomy is entering an era in which gravitational waves and neutrinos will be used to complement existing techniques and to uncover the hidden features of our Universe.

    • Mark Zastrow
    Outlook