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Leukaemic cells and normal blood-producing cells relate differently to their surroundings. This concept has now been extended to leukaemic stem cells, suggesting a fresh approach to therapy.
Nerve impulses that convey pain signals to the brain are produced by sodium channels in the neuronal membrane. Studies on people who are unable to feel pain identify one specific sodium channel as essential to the process.
Fabricating large-scale semiconducting surfaces for the flexible screens of the future is a bothersome business. A simple technique for growing single-crystal organic semiconductors brings new vision to the field.
Observations of a phenomenon known as the magnetic fountain effect in superfluid helium are not just beautiful experiments, but could also supply a tool for studying many other exotic magnetic phenomena.
Researchers aren't the only ones who concern themselves with animal welfare in the lab. Vets are asked regularly to monitor and care for these animals — a role that can call for some difficult decisions. Kerri Smith talks to Sarah Wolfensohn, head of veterinary services at the University of Oxford, UK, about the challenges and conflicts presented by caring for experimental animals.
Inhibition of the insulin-signalling pathway leads to insulin resistance, an early step in the development of type 2 diabetes. A novel family of protein activators seems to act near the pathway's inception.
Primate researchers have long faced violent protests over their work. But in some countries, regulatory obstacles are taking a greater toll. David Cyranoski meets European scientists who feel that bureaucratic pressures are closing their labs.
How much momentum does light transfer to a material through which it passes? This is a surprisingly opaque matter, contested for almost a century, that is still the object of theory and experimentation.