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  • Single-cell RNA sequencing and 3D imaging have revealed the cellular changes and structural reorganization that occur during the progression of human chronic liver disease and as the liver attempts to regenerate.

    • Christopher Gribben
    • Vasileios Galanakis
    • Ludovic Vallier
    ArticleOpen Access
  • Stable chelation of the 147Pm radionuclide in aqueous solution by the newly synthesized organic diglycolamide ligand is demonstrated and the resulting complex studied, showing accelerated shortening of bonds at the beginning of the lanthanide series.

    • Darren M. Driscoll
    • Frankie D. White
    • Alexander S. Ivanov
    ArticleOpen Access
  • Recovered cement paste can be reclinkered if used as a partial substitute for the lime–dolomite flux used in steel recycling, which can reduce waste and carbon emissions.

    • Cyrille F. Dunant
    • Shiju Joseph
    • Julian M. Allwood
    ArticleOpen Access
  • Structures of the kainate receptor GluK2 with and without concanavilin A and BPAM344 show how these ligands modulate channel activity and reveal the molecular basis of kainate receptor gating.

    • Shanti Pal Gangwar
    • Maria V. Yelshanskaya
    • Alexander I. Sobolevsky
    ArticleOpen Access
  • Structural analysis of the human choline and ethanolamine transporters FLVCR1 and FLVCR2 clarifies the mechanisms of transport, the conformational dynamics of these proteins and the disease-associated mutations that interfere with these processes.

    • Keiken Ri
    • Tsai-Hsuan Weng
    • Schara Safarian
    ArticleOpen Access
  • Stretchable radio-frequency electronics based on a dielectro-elastic elastomer is demonstrated to be capable of completely maintaining operating frequencies unaffected by strain and shows superior electrical, mechanical and thermal properties compared with conventional stretchable substrate materials.

    • Sun Hong Kim
    • Abdul Basir
    • Yei Hwan Jung
    Article
  • Cement can be reused by including it as a component of steel recycling. This opens the way to an industrial partnership that improves the use of materials and lowers carbon emissions — but only if waste resources are well managed.

    • Sabbie A. Miller
    News & Views
  • Neuroscientists find that two distinct neural pathways are responsible for the addictive properties of the opioid fentanyl: one mediates reward, the other promotes the seeking of relief from symptoms of withdrawal.

    • Markus Heilig
    • Michele Petrella
    News & Views
  • A phenomenon that affects the magnetic fields of rotating bodies could be involved in recurring changes in the Sun’s behaviour, which are related to a periodic flipping of its field. The proposal is a fresh take on this strange effect.

    • Ellen Zweibel
    News & Views
  • Solving problems in a safe, collaborative environment can help us think out of the box and build empathy — crucial skills in a warming world.

    • Sam Illingworth
    World View