Articles in 2022

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  • Jonathan Park’s scientific interests changed after caring for a person with cancer. He ended up bidding an amicable farewell to Mark Gerstein, a supportive supervisor who had taught him a lot.

    • Jonathan Park
    • Mark Gerstein
    Career Column
  • A measure of last resort got a major workout during the pandemic. Scientists are now trying to determine whether the benefits outweighed the potential damage to public trust.

    • Liam Drew
    News Feature
  • Enzymes use molecular clusters containing iron and sulfur atoms to bind and ‘fix’ nitrogen gas into a bioavailable form. A synthetic cluster that binds and reduces nitrogen molecules casts light on the mechanism of fixation.

    • Daniël L. J. Broere
    News & Views
  • Quantum entanglement has been generated between two single-atom quantum memories over a 33-kilometre optical-fibre link. The wavelength of the photons emitted by these quantum memories was converted to one that works in telecommunications without altering the polarization of the photons, paving the way for the long-distance links of future quantum networks.

    Research Briefing
  • The first cloned mice from skin cells that had been freeze-dried for up to nine months. Plus, what to expect from the revved-up LHC and what the data say about whether COVID passes and vaccine mandates work.

    • Flora Graham
    Nature Briefing
  • Swirling vortices have been directly observed in a flow of electric current for the first time. Unlike conventional viscous fluids, collective fluid-like behaviour in this case is not caused by particle–particle collisions, but results from a previously unidentified mechanism involving single electrons scattering from material surfaces at small angles.

    Research Briefing
  • A mechanism resembling a crankshaft switches the electric polarization of a material in response to changes in an applied magnetic field. The resulting four-state switch is linked to the material’s intriguing topology.

    • Wei Ren
    • Laurent Bellaiche
    News & Views
  • Adolescence is an intensely stressful life stage. We developed a brief online training module to help young people to understand stress and to respond to it constructively. The module improved their psychological and physiological responses to stress and boosted academic performance.

    Research Briefing
  • Lung samples housed in medical archives have yielded three genomes for the influenza A virus that caused the 1918 global pandemic. The sequences reveal mutations that might have triggered the pandemic’s devastating second wave.

    • Martha I. Nelson
    • Elodie Ghedin
    News & Views
  • This study provides a comprehensive spatiotemporal map of human and mouse gonadal differentiation, using a combination of single-cell and spatial transcriptomics, chromatin accessibility assays and fluorescent microscopy, which can guide in vitro gonadogenesis.

    • Luz Garcia-Alonso
    • Valentina Lorenzi
    • Roser Vento-Tormo
    ArticleOpen Access
  • Active super-enhancers are highly and specifically hypermutated in 92% of diffuse large B cell lymphoma samples and display signatures of activation-induced cytidine deaminase activity, leading to the dysregulation of genes encoding B cell developmental regulators and oncogenes.

    • Elodie Bal
    • Rahul Kumar
    • Riccardo Dalla-Favera
    Article