Analyses in 2021

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  • An economic analysis suggests that targeting aging offers potentially larger economic gains than eradicating individual diseases. Slowing aging to increase life expectancy by 1 year is worth US$38 trillion, and by 10 years, US$367 trillion.

    • Andrew J. Scott
    • Martin Ellison
    • David A. Sinclair
    AnalysisOpen Access
  • Using genetic and demographic data from the UK Biobank, the authors clustered 116 common diseases based on their age-of-onset profiles and found increased genetic similarity within clusters, suggesting common etiologies. Two of the four disease clusters were associated with aging-related genes but differed in functional enrichment and evolutionary profiles.

    • Handan Melike Dönertaş
    • Daniel K. Fabian
    • Janet M. Thornton
    Analysis