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Cancer & Aging Collection
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Progress towards the Sustainable Development Goals
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Hearing loss promotes Alzheimer’s disease
Epidemiological studies reveal a correlation between hearing loss and the development and progression of Alzheimer’s disease (AD), but the underlying causal mechanisms remain unclear. A study now provides experimental evidence that hearing loss can promote AD via the growth differentiation factor 1 (GDF1) pathway, which may aid in developing potential AD therapeutic strategies.
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Aging, longevity and age-related diseases
Our understanding of the biology of aging and longevity has grown tremendously over the past two decades.
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Leveraging electronic health records and knowledge networks for Alzheimer’s disease prediction and sex-specific biological insights
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Targeting the biology of aging with mTOR inhibitors
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Age-dependent loss of HAPLN1 erodes vascular integrity via indirect upregulation of endothelial ICAM1 in melanoma
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Mechanisms of melanoma aggressiveness with age