Volume 51 Issue 4, April 2022

Teamwork and organizational culture have been increasingly recognized as essential components to improving healthcare. Given the stakeholders and complexity of work necessary to execute high-quality animal research, creating a strong, high-performing team of clinicians, scientists and veterinarians would improve productivity. Positive collaborative cultures can advance animal and human welfare, enhance research quality and provide mutual learning for all team members.

This protocol describes an in vivo cartilage formation assay. Human or bovine articular chondrocytes injected in nude mice form cartilage organoids that can be used for the screening of molecules that promote cartilage formation.