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Magnetic resonance imaging (MRI) is a non-invasive imaging modality that can help bridge neuroscience research in nonhuman primates with the humans they are intended to model. But, studies with such animals tend to involve small numbers of subjects, and the task of adapting human equipment and tools to nonhuman primates means labs are often coming up with their own solutions to collecting and analyzing MRI data. Data sharing may help researchers make the most of those animals. With discussions about standards and tool building ongoing, a growing number of labs in the nonhuman primate research community are working to bring their MRI datasets together.
Strain contributions arising from the strain of origin and backcrosses can modify phenotypic severity and/or penetrance of mutant alleles in mouse models.
University College London’s Carole Wilson talks to Lab Animal about how she and her fish facility staff have responded to the ongoing coronavirus pandemic.
Christine Archer, fish facility coordinator at the University of Colorado Anschutz Medical Campus, walks Lab Animal through her facility’s response to the ongoing coronavirus pandemic.
To bridge brains and make the most of their nonhuman primate models, neuroscientists are setting standards, building tools, and starting to share their neuroimaging data.