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Nature Reviews Drug Discovery Nature Reviews Genetics
Nature Reviews Drug Discovery and Nature Reviews Genetics present a joint Focus on Pharmacogenetics, which examines the role of genetics in determining how patients respond to drug treatment. The Focus provides a comprehensive collection of articles on the development of pharmacogenetics, covering topics ranging from the latest approaches in pharmacogenetics research to evolving regulatory frameworks and ethical issues. The articles on this page were made freely available from September 2004 to November 2004.
research highlights
Lack of data privacy could hamper pharmacogenomics studies Lack of data privacy could hamper pharmacogenomics studies
Individuals could be identified from medically relevant genomic sequences stored in databases.... [more]
perspective

Opinion: Genetically modified mouse models for pharmacogenomic research
Stephen B. Liggett
Abstract | Full Text | PDF

Science and Society: Integrating pharmacogenetics into society: in search of a model
Andrew Webster, Paul Martin, Graham Lewis & Andrew Smart
Abstract | Full Text | PDF

Timeline: Pharmacogenetics - five decades of therapeutic lessons from genetic diversity
Urs A. Meyer
Abstract | Full Text | PDF

Viewpoint: Pharmacogenetics: ethical problems and solutions
Alasdair Breckenridge, Klaus Lindpaintner, Peter Lipton, Howard McLeod, Mark Rothstein & Helen Wallace
Abstract | Full Text | PDF

Opinion: Translation of pharmacogenomics and pharmacogenetics: a regulatory perspective
Lawrence J. Lesko & Janet Woodcock
Abstract | Full Text | PDF

reviews

Pharmacogenetics and drug development: the path to safer and more effective drugs
Allen D. Roses
Abstract | Full Text | PDF

Pharmacogenomics: bench to bedside
Richard Weinshilboum & Liewei Wang
Abstract | Full Text | PDF

Technology platforms for pharmacogenomic diagnostic assays
Walter H. Koch
Abstract | Full Text | PDF

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