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EDITOR'S CHOICE 2010
Cell Research is proud to present a collection of featured articles from 2010 that represent a broad scope in basic molecular and cell biology research. These articles have been chosen by the Editor to illustrate some of the latest developments over a range of topics, including cell growth and differentiation, signal transduction, stem cells, immunology, neurosciences, chromatin modulation, epigenetics and transcription.
Reviews
Molecular basis of the first cell fate determination in mouse embryogenesis FREE
Lingyi Chen, Dekun Wang, Zhaoting Wu, Liping Ma and George Q Daley
Cell Res 20: 982-993; advance online publication, July 13, 2010; doi:10.1038/cr.2010.106
Overview of macroautophagy regulation in mammalian cells FREE
Maryam Mehrpour, Audrey Esclatine, Isabelle Beau and Patrice Codogno
Cell Res 20: 748-762; advance online publication, June 15, 2010; doi:10.1038/cr.2010.82
Endocytosis unplugged: multiple ways to enter the cell FREE
Sudha Kumari, Swetha MG and Satyajit Mayor
Cell Res 20: 256-275; advance online publication, February 2, 2010; doi:10.1038/cr.2010.19
Heterogeneity and plasticity of T helper cells FREE
Jinfang Zhu and William E Paul
Cell Res 20: 4-12; advance online publication, December 15, 2009; doi:10.1038/cr.2009.138
Original Articles
Chemical probing reveals insights into the signaling mechanism of inflammasome activation FREE
Yi-Nan Gong, Xiaoming Wang, Jiayi Wang, Zhenxiao Yang, Shan Li, Jieling Yang, Liping Liu, Xiaoguang Lei and Feng Shao
Cell Res 20: 1289-1305; advance online publication, September 21, 2010; doi:10.1038/cr.2010.135
BRCA1 affects global DNA methylation through regulation of DNMT1 FREE
Vivek Shukla, Xavier Coumoul, Tyler Lahusen, Rui-Hong Wang, Xiaoling Xu, Athanassios Vassilopoulos, Cuiying Xiao, Mi-Hye Lee, Yan-Gao Man, Mutsuko Ouchi, Toru Ouchi and Chu-Xia Deng
Cell Res 20: 1201-1215; advance online publication, September 7, 2010; doi:10.1038/cr.2010.128
Tom70 mediates activation of interferon regulatory factor 3 on mitochondria FREE
Xin-Yi Liu, Bo Wei, He-Xin Shi, Yu-Fei Shan and Chen Wang
Cell Res 20: 994-1011; advance online publication, July 13, 2010; doi:10.1038/cr.2010.103
Dynamic regulation of alternative splicing and chromatin structure in Drosophila gonads revealed by RNA-seq FREE
Qiang Gan, Iouri Chepelev, Gang Wei, Lama Tarayrah, Kairong Cui, Keji Zhao and Xin Chen
Cell Res 20: 763-783; advance online publication, May 4, 2010; doi:10.1038/cr.2010.64
A de novo originated gene depresses budding yeast mating pathway and is repressed by the protein encoded by its antisense strand FREE
Dan Li, Yang Dong, Yu Jiang, Huifeng Jiang, Jing Cai and Wen Wang
Cell Res 20: 408-420; advance online publication, March 2, 2010; doi:10.1038/cr.2010.31
Dual-specificity histone demethylase KIAA1718 (KDM7A) regulates neural differentiation through FGF4 FREE
Chengyang Huang, Yang Xiang, Yanru Wang, Xia Li, Longyong Xu, Ziqi Zhu, Ting Zhang, Qingqing Zhu, Kejing Zhang, Naihe Jing and Charlie Degui Chen
Cell Res 20: 154-165; advance online publication, January 19, 2010; doi:10.1038/cr.2010.5
A GPCR/secretase complex regulates β- and γ-secretase specificity for Aβ production and contributes to AD pathogenesis FREE
Lin Teng, Jian Zhao, Feifei Wang, Lan Ma and Gang Pei
Cell Res 20: 138-153; advance online publication, January 12, 2010; doi:10.1038/cr.2010.3
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