The chimpanzee genome

In this focus:

Current research | Archive

What makes us human? We share more than 98% of our DNA and almost all of our genes with our closest living relative, the chimpanzee. Comparing the genetic code of humans and chimps will allow the study of not only our similarities, but also the minute differences that set us apart.

Providing a resource for more than just genomics, Nature presents a special web focus to commemorate the genome of Pan troglodytes. Alongside the first unequivocal fossil evidence of the genus Pan, leading researchers have kindly supplied Nature with previously-unseen film of experiments and observations of chimps in the wild and from world-renowned sanctuaries. Selected films relate to papers published in the chimp genome special issue. Enjoy FREE ACCESS to an incredible gallery of chimpanzee behaviour courtesy of Nature and the people behind the science.

For news, interactive graphics, features, a roll call of famous chimps and more, see news@nature.com's chimp genome special

World Atlas of Great Apes and their Conservation launches in London on Thursday 1st September 2005. For more information, click here.


Current research


The chimpanzee genome

Chris Gunter and Ritu Dhand

Nature 437, 47 (1 September 2005) doi:10.1038/437047a


A brief history of the chimp

Nature 437, 48–49 (1 September 2005) doi:10.1038/437048a


The chimpanzee and us

Wen-Hsiung Li and Matthew A. Saunders

Nature 437, 50–51 (1 September 2005) doi:10.1038/437050a


The second inheritance system of chimpanzees and humans

A Whiten

Nature 437, 52–55 (1 September 2005) doi:10.1038/nature04023

A century of getting to know the chimpanzee

F B M de Waal

Nature 437, 56–59 (1 September 2005) doi:10.1038/nature03999

Our chimpanzee mind

M Hauser

Nature 437, 60–63 (1 September 2005) doi:10.1038/nature03917

Molecular insights into human brain evolution

R S Hill and Ch A Walsh

Nature 437, 64–68 (1 September 2005) doi:10.1038/nature04103


Initial sequence of the chimpanzee genome and comparison with the human genome Free access

The Chimpanzee Sequencing and Analysis Consortium

Nature 437, 69–87 (1 September 2005) doi:10.1038/nature04072

A genome-wide comparison of recent chimpanzee and human segmental duplications Free access

Z Cheng et al.

Nature 437, 88–93 (1 September 2005) doi:10.1038/nature04000

Human subtelomeres are hot spots of interchromosomal recombination and segmental duplication Free access

E V Linardopoulou et al.

Nature 437, 94–100 (1 September 2005) doi:10.1038/nature04029


Conservation of Y-linked genes during human evolution revealed by comparative sequencing in chimpanzee Free access

J F. Hughes et al.

Nature 437, 101–104 (1 September 2005) doi:10.1038/nature04101

First fossil chimpanzee

S McBrearty and N G Jablonski

Nature 437, 104–108 (1 September 2005) doi:10.1038/nature04008




All's fair between friendly chimps

Jessica Ebert

news@nature.com (26 January 2005) doi:10.1038/news050124-7

Bonobos face extinction

Michael Hopkin

news@nature.com (10 December 2004) doi:10.1038/news041206-16

Girl chimps learn faster than boys

Daughters pick up their mother's skills, while sons play rough and tumble.

Michael Hopkin

Published online: 15 April 2004 doi:10.1038/news040412-6

Geneticists study chimp–human divergence

Erika Check

Nature 428, 242 (18 March 2004) doi:10.1038/428242a

Genome scan shows human-chimp differences

Variations hint at how our lifestyle is reflected in our genes.

John Whitfield

Published online: 12 December 2003 doi:10.1038/news031208-15

Chimps expose humanness

Preliminary genome comparison points to primate individuality.

Helen Pearson

Published online: 29 April 2003 doi:10.1038/news030428-3


Chimpanzee genome: Almost human...

Sequencing the chimpanzee has emerged as a top genomic priority. David Cyranoski asks the chimp's champions what they hope to gain from studying the genome of our closest living relative.

Nature 418, 910-912 (29 August 2002) doi:10.1038/418910a


Primate viewing

Tetsuro Matsuzawa

Nature 434, 21 - 22 (03 March 2005) doi:10.1038/434021a


Animal behaviour: Congo's art

Tim Lincoln

Nature 435, 1040 (23 June 2005) doi:10.1038/4351040b

Genome sequencing: Differences with the relatives

Jean Weissenbach

Nature 429, 353-355 (27 May 2004) doi:10.1038/429353a

Evolutionary biology: Our relative genetics

David Penny

Nature 427, 208-209 (15 January 2004) doi:10.1038/427208a


Sex differences in learning in chimpanzees

Elizabeth V. Lonsdorf, Lynn E. Eberly and Anne E. Pusey

Nature 428, 715-716 (15 April 2004) doi:10.1038/428715a


Genomic strategies to identify mammalian regulatory sequences

Len A. Pennacchio and Edward M. Rubin

Nature Reviews Genetics 2, 100-109 (2001); doi:10.1038/ doi:10.1038/35052548


DNA sequence and comparative analysis of chimpanzee chromosome 22 Free access

The International Chimpanzee Chromosome 22 Consortium

Nature 429, 382-388 (27 May 2004) doi:10.1038/nature02564


Fine-scale recombination patterns differ between chimpanzees and humans

Susan E Ptak et al.

Nature Genetics 37, 429-434 (February 2005) doi:10.1038/ng1529

Myosin gene mutation correlates with anatomical changes in the human lineage

Hansell H. Stedman et al.

Nature 428, 415-418 (25 March 2004) doi:10.1038/nature02358