Focus

Focus on Autophagy

Autophagy targets damaged organelles and proteins for lysosomal degradation. This potent degradation mechanism has crucial roles in development, immune defence, programmed cell death, tumour suppression, neurodegeneration and stress response. The September 2010 issue of Nature Cell Biology presents a series of specially commissioned Reviews, Perspectives and Commentaries highlighting new insights into this process.

Editorial

Focus on Autophagy

Focusing on Autophagy

Nature Cell Biology 12, p 813; (2010)


Reviews

Focus on Autophagy

Eaten alive: a history of macroautophagy

Zhifen Yang & Daniel J. Klionsky

Nature Cell Biology 12, pp 814–822; (2010)

Focus on Autophagy

Autophagy in mammalian development and differentiation

Noboru Mizushima & Beth Levine

Nature Cell Biology 12, pp 823–830; (2010)

Perspectives

Focus on Autophagy

The origin of the autophagosomal membrane

Sharon A. Tooze & Tamotsu Yoshimori

Nature Cell Biology 12, pp 831–835; (2010)

Focus on Autophagy

Selective autophagy: ubiquitin-mediated recognition and beyond

Claudine Kraft, Matthias Peter & Kay Hofmann

Nature Cell Biology 12, pp 836–841; (2010)

Commentary

Focus on Autophagy

Can autophagy promote longevity?

Frank Madeo, Nektarios Tavernarakis & Guido Kroemer

Nature Cell Biology 12, pp 842–846; (2010)