Nature Outline 

Ulcerative colitis

Ulcerative colitis is a debilitating and incurable condition. But researchers have found fresh angles of attack, and a host of upcoming treatments raise the prospect of a durable victory against this common form of inflammatory bowel disease.

This Nature Outline is editorially independent. It is produced with third party financial support. About this content.

This Nature Outline is editorially independent, produced with financial support from a third party. About this content.

Ulcerative colitis: Fresh approaches to taming inflammation

Ulcerative colitis is a common form of inflammatory bowel disease. For many people with the condition, widely prescribed anti-inflammatory or immunosuppressive drugs do not remain effective for long, and up to 15% of patients will need surgery to remove all or part of the colon within 20 years of diagnosis. This animation explores how insights into the immunobiology of ulcerative colitis are helping researchers to develop innovative treatments.