Collection 

Gene therapy for cancer

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Open
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Gene therapy is a therapeutic method that modifies an individual’s genes to correct an underlying genetic problem. Cancer is often described as a genetic disease, with many cancers being driven by specific genetic lesions. Therefore, gene therapy might be particularly useful in treating cancer. Gene therapy can take many forms in cancer: gene editing can be used restore mutated oncogenes or tumor suppressors, suicide gene therapy can be used to promote cancer cell apoptosis, and T cells can be engineered for precision therapy through the introduction of chimeric antigens. Clinically, however, few gene-editing treatments have been approved for use in cancer patients, indicating the need for more research into this therapeutic modality.

This Collection welcomes original research examining gene therapy in cancer, including preclinical and clinical studies on gene editing and delivery and chimeric antigen receptor T cells.

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Genetic engineering and gene manipulation concept. Hand is replacing part of a DNA molecule.

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Submitting a paper for consideration

 

To submit your manuscript for consideration at Scientific Reports as part of this Collection, please follow the steps detailed on this page. On the first page of our online submission system, under “I’m submitting:” select the option “any other article type”. Once logged in you can submit your manuscript to a Collection by selecting “Guest Edited Collection”, under the “Choose the appropriate manuscript type” message, and clicking “Continue”. Then when filling out the manuscript information, select the "Gene therapy for cancer" Collection from the alphabetical list on the “Springer Nature Subject Category” tab. Authors should express their interest in the Collection in their cover letter.

Accepted papers are published on a rolling basis as soon as they are ready.

In addition to papers on Gene therapy for cancer, Scientific Reports welcomes all original research in the field of Cell biology . To browse our latest articles in Cell biology click here.

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