Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain
the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in
Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles
and JavaScript.
Through mechanotransduction, organisms are able to respond to mechanical stimuli in the environment, with a physical input being converted into biochemical signalling, leading to a cellular response. These mechanical stimuli guide a range of inter and intracellular decisions and activities, however the underlying molecular mechanisms and sensors responsible are not yet fully characterised.
This Collection will bring together studies which advance our understanding of the mechanisms that underlie mechanotransduction at a cellular level, as well as those that explore how mechanotransduction relates to health and disease.